Central Activation of Alpha7 Nicotinic Signaling Attenuates LPS-Induced Neuroinflammation and Sickness Behavior in Adult but Not in Aged Animals

gan Navarro, Elisa, Norden, Diana M., Trojanowski, Paige J., Godbout, Jonathan P., López, Manuela G.
Cyhoeddwyd yn Molecules (2021)

Enantioselective Neuroprotective Effects of Tacripyrine ITH122 Against Oxygen and Glucose Deprivation in Rat Hippocampal Slices

gan Romero, Alejandro, Gomez‐Rangel, Vanessa, Egea, Javier, Samadi, Abdelouahid, Marco‐Contelles, José, Lopez, Manuela G.
Cyhoeddwyd yn CNS Neurosci Ther (2013)

Aging and Progression of Beta-Amyloid Pathology in Alzheimer’s Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression

gan Fernández-Mendívil, Cristina, Arreola, Miguel A., Hohsfield, Lindsay A., Green, Kim N., Lopez, Manuela G.
Cyhoeddwyd yn Antioxidants (Basel) (2020)

Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism

gan Fernández-Mendívil, Cristina, Luengo, Enrique, Trigo-Alonso, Paula, García-Magro, Nuria, Negredo, Pilar, López, Manuela G.
Cyhoeddwyd yn Redox Biol (2020)

Data supporting the rat brain sample preparation and validation assays for simultaneous determination of 8 neurotransmitters and their metabolites using liquid chromatography–tande...

gan Wojnicz, Aneta, Ortiz, José Avendaño, Casas, Ana I., Freitas, Andiara E., López, Manuela G., Ruiz-Nuño, Ana
Cyhoeddwyd yn Data Brief (2016)

Calcium signalling mediated through α7 and non-α7 nAChR stimulation is differentially regulated in bovine chromaffin cells to induce catecholamine release

gan del Barrio, Laura, Egea, Javier, León, Rafael, Romero, Alejandro, Ruiz, Ana, Montero, Mayte, Álvarez, Javier, López, Manuela G
Cyhoeddwyd 2011

The Microglial α7-Acetylcholine Nicotinic Receptor Is a Key Element in Promoting Neuroprotection by Inducing Heme Oxygenase-1 via Nuclear Factor Erythroid-2-Related Factor 2

gan Parada, Esther, Egea, Javier, Buendia, Izaskun, Negredo, Pilar, Cunha, Ana C., Cardoso, Silvia, Soares, Miguel P., López, Manuela G.
Cyhoeddwyd 2013

Redox Control of Microglial Function: Molecular Mechanisms and Functional Significance

gan Rojo, Ana I., McBean, Gethin, Cindric, Marina, Egea, Javier, López, Manuela G., Rada, Patricia, Zarkovic, Neven, Cuadrado, Antonio
Cyhoeddwyd 2014

Melatonin–sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a ‘drug–prodrug’ mechanism of action

gan Egea, Javier, Buendia, Izaskun, Parada, Esther, Navarro, Elisa, Rada, Patricia, Cuadrado, Antonio, López, Manuela G, García, Antonio G, León, Rafael
Cyhoeddwyd yn Br J Pharmacol (2015)

Effects of the neuroprotectant lubeluzole on the cytotoxic actions of veratridine, barium, ouabain and 6-hydroxydopamine in chromaffin cells

gan Cano-Abad, María F, López, Manuela G, Hernández-Guijo, Jesús M, Zapater, Pedro, Gandía, Luis, Sánchez-García, Pedro, García, Antonio G
Cyhoeddwyd 1998

Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy

gan Rojo, Ana I., Pajares, Marta, García-Yagüe, Angel J., Buendia, Izaskun, Van Leuven, Fred, Yamamoto, Masayuki, López, Manuela G., Cuadrado, Antonio
Cyhoeddwyd yn Redox Biol (2018)

CALHM1 and its polymorphism P86L differentially control Ca(2+) homeostasis, mitogen‐activated protein kinase signaling, and cell vulnerability upon exposure to amyloid β

gan Moreno‐Ortega, Ana José, Buendia, Izaskun, Mouhid, Lamia, Egea, Javier, Lucea, Susana, Ruiz‐Nuño, Ana, López, Manuela G., Cano‐Abad, María F.
Cyhoeddwyd yn Aging Cell (2015)

Antioxidant, Anti-inflammatory and Neuroprotective Profiles of Novel 1,4-Dihydropyridine Derivatives for the Treatment of Alzheimer’s Disease

gan Michalska, Patrycja, Mayo, Paloma, Fernández-Mendívil, Cristina, Tenti, Giammarco, Duarte, Pablo, Buendia, Izaskun, Ramos, María Teresa, López, Manuela G., Menéndez, J. Carlos, León, Rafael
Cyhoeddwyd yn Antioxidants (Basel) (2020)

Modulatory Mechanism of the Endogenous Peptide Catestatin on Neuronal Nicotinic Acetylcholine Receptors and Exocytosis

gan Herrero, Carlos J., Alés, Eva, Pintado, Antonio J., López, Manuela G., García-Palomero, Esther, Mahata, Sushil K., O'Connor, Daniel T., García, Antonio G., Montiel, Carmen
Cyhoeddwyd yn J Neurosci (2002)

PF9404C, a new slow NO donor with beta receptor blocking properties

gan Villarroya, Mercedes, Herrero, Carlos J, Ruíz-Nuño, Ana, de Pascual, Ricardo, del Valle, Mercedes, Michelena, Pedro, Grau, Manuel, Carrasco, Emilio, López, Manuela G, García, Antonio G
Cyhoeddwyd 1999

Voltage inactivation of Ca(2+) entry and secretion associated with N- and P/Q-type but not L-type Ca(2+) channels of bovine chromaffin cells

gan Villarroya, Mercedes, Olivares, Román, Ruíz, Ana, Cano-Abad, María F, de Pascual, Ricardo, Lomax, Richard B, López, Manuela G, Mayorgas, Inés, Gandía, Luis, García, Antonio G
Cyhoeddwyd 1999

Both Creatine and Its Product Phosphocreatine Reduce Oxidative Stress and Afford Neuroprotection in an In Vitro Parkinson’s Model

gan Cunha, Mauricio Peña, Martín-de-Saavedra, Maria D., Romero, Alejandro, Egea, Javier, Ludka, Fabiana K., Tasca, Carla I., Farina, Marcelo, Rodrigues, Ana Lúcia S., López, Manuela G.
Cyhoeddwyd yn ASN Neuro (2014)

NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage

gan Casas, Ana I., Geuss, Eva, Kleikers, Pamela W. M., Mencl, Stine, Herrmann, Alexander M., Buendia, Izaskun, Egea, Javier, Meuth, Sven G., Lopez, Manuela G., Kleinschnitz, Christoph, Schmidt, Harald H. H. W.
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2017)

A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection

gan Langhauser, Friederike, Casas, Ana I., Dao, Vu-Thao-Vi, Guney, Emre, Menche, Jörg, Geuss, Eva, Kleikers, Pamela W. M., López, Manuela G., Barabási, Albert-L., Kleinschnitz, Christoph, Schmidt, Harald H. H. W.
Cyhoeddwyd yn NPJ Syst Biol Appl (2018)

From single drug targets to synergistic network pharmacology in ischemic stroke

gan Casas, Ana I., Hassan, Ahmed A., Larsen, Simon J., Gomez-Rangel, Vanessa, Elbatreek, Mahmoud, Kleikers, Pamela W. M., Guney, Emre, Egea, Javier, López, Manuela G., Baumbach, Jan, Schmidt, Harald H. H. W.
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2019)