A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection

Network medicine utilizes common genetic origins, markers and co-morbidities to uncover mechanistic links between diseases. These links can be summarized in the diseasome, a comprehensive network of disease–disease relationships and clusters. The diseasome has been influential during the past decade...

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Detalhes bibliográficos
Publicado no:NPJ Syst Biol Appl
Main Authors: Langhauser, Friederike, Casas, Ana I., Dao, Vu-Thao-Vi, Guney, Emre, Menche, Jörg, Geuss, Eva, Kleikers, Pamela W. M., López, Manuela G., Barabási, Albert-L., Kleinschnitz, Christoph, Schmidt, Harald H. H. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799370/
https://ncbi.nlm.nih.gov/pubmed/29423274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-017-0039-7
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