Effects of the neuroprotectant lubeluzole on the cytotoxic actions of veratridine, barium, ouabain and 6-hydroxydopamine in chromaffin cells

1. Incubation of bovine adrenal chromaffin cells with veratridine (10–100 μM) during 24 h, caused a concentration-dependent release of the cytosolic lactate dehydrogenase (LDH) into the bathing medium, an indicator of cell death. Lubeluzole or its R(−) enantiomer, R91154, did not enhance LDH release...

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Detalles Bibliográficos
Autores principales: Cano-Abad, María F, López, Manuela G, Hernández-Guijo, Jesús M, Zapater, Pedro, Gandía, Luis, Sánchez-García, Pedro, García, Antonio G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565510/
https://ncbi.nlm.nih.gov/pubmed/9720790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701955
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