The Autophagic Lysosomal System in Outflow Pathway Physiology and Pathophysiology

por Liton, Paloma B.
Publicado en Exp Eye Res (2015)

Stress Response of the Trabecular Meshwork

por Liton, Paloma B., Gonzalez, Pedro
Publicado 2008

AUTOPHAGY AND MECHANOTRANSDUCTION IN OUTFLOW PATHWAY CELLS

por Hirt, Joshua, Liton, Paloma B.
Publicado en Exp Eye Res (2016)

Cathepsin B Is Up-Regulated and Mediates Extracellular Matrix Degradation in Trabecular Meshwork Cells Following Phagocytic Challenge

por Porter, Kristine, Lin, Yizhi, Liton, Paloma B.
Publicado 2013

THE ROLE OF PROTEOLYTIC CELLULAR SYSTEMS IN TRABECULAR MESHWORK HOMEOSTASIS

por Liton, Paloma B., Gonzalez, Pedro, Epstein, David L.
Publicado 2008

Intralysosomal Iron Induces Lysosomal Membrane Permeabilization and Cathepsin D–Mediated Cell Death in Trabecular Meshwork Cells Exposed to Oxidative Stress

por Lin, Yizhi, Epstein, David L., Liton, Paloma B.
Publicado 2010

mTOR-INDEPENDENT INDUCTION OF AUTOPHAGY IN TRABECULAR MESHWORK CELLS SUBJECTED TO BIAXIAL STRETCH

por Porter, Kristine M., Jeyabalan, Nallathambi, Liton, Paloma B.
Publicado 2014

Up-Regulated Expression of Extracellular Matrix Remodeling Genes in Phagocytically Challenged Trabecular Meshwork Cells

por Porter, Kristine M., Epstein, David L., Liton, Paloma B.
Publicado 2012

Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: Implications for glaucoma pathogenesis

por Porter, Kristine, Nallathambi, Jeyabalan, Lin, Yizhi, Liton, Paloma B.
Publicado 2013

Ascorbic Acid Modulation of Iron Homeostasis and Lysosomal Function in Trabecular Meshwork Cells

por Xu, Ping, Lin, Yizhi, Porter, Kristine, Liton, Paloma B.
Publicado 2014

Potential role of lysosomal dysfunction in the pathogenesis of primary open angle glaucoma

por Liton, Paloma B., Lin, Yizhi, Gonzalez, Pedro, Epstein, David L.
Publicado 2009

Autophagic Dysregulation in Glaucomatous Trabecular Meshwork Cells

por Porter, Kristine, Hirt, Joshua, Stamer, W. Daniel, Liton, Paloma B.
Publicado en Biochim Biophys Acta (2014)

Transcriptome analysis reveals autophagy as regulator of TGFβ/Smad-induced fibrogenesis in trabecular meshwork cells

por Nettesheim, April, Shim, Myoung Sup, Hirt, Josh, Liton, Paloma B.
Publicado en Sci Rep (2019)

The autophagic protein LC3 translocates to the nucleus and localizes in the nucleolus associated to NUFIP1 in response to cyclic mechanical stress

por Shim, Myoung Sup, Nettesheim, April, Hirt, Joshua, Liton, Paloma B.
Publicado en Autophagy (2019)

Primary cilia and the reciprocal activation of AKT and SMAD2/3 regulate stretch-induced autophagy in trabecular meshwork cells

por Shim, Myoung Sup, Nettesheim, April, Dixon, Angela, Liton, Paloma B.
Publicado en Proc Natl Acad Sci U S A (2021)

Effect of cellular senescence on the P2Y-receptor mediated calcium response in trabecular meshwork cells

por Chow, Jessica, Liton, Paloma B., Luna, Coralia, Wong, Fulton, Gonzalez, Pedro
Publicado 2007

Cross-talk between TGF-β1 and IL-6 in human trabecular meshwork cells

por Liton, Paloma B., Li, Guorong, Luna, Coralia, Gonzalez, Pedro, Epstein, David L.
Publicado 2009

Alterations in gene expression induced by cyclic mechanical stress in trabecular meshwork cells

por Luna, Coralia, Li, Guorong, Liton, Paloma B., Epstein, David L., Gonzalez, Pedro
Publicado 2009

Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue

por Liton, Paloma B., Luna, Coralia, Challa, Pratap, Epstein, David L., Gonzalez, Pedro
Publicado 2006

Contribution of autophagy to ocular hypertension and neurodegeneration in the DBA/2J spontaneous glaucoma mouse model

por Hirt, Joshua, Porter, Kris, Dixon, Angela, McKinnon, Stuart, Liton, Paloma B.
Publicado en Cell Death Discov (2018)