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Transcriptome analysis reveals autophagy as regulator of TGFβ/Smad-induced fibrogenesis in trabecular meshwork cells

The trabecular meshwork (TM) is a specialized ocular tissue, which is responsible, together with the Schlemm’s canal (SC), for maintaining appropriate levels of intraocular pressure. Dysfunction of these tissues leads to ocular hypertension and increases the risk for developing glaucoma. Previous wo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nettesheim, April, Shim, Myoung Sup, Hirt, Josh, Liton, Paloma B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834604/
https://ncbi.nlm.nih.gov/pubmed/31695131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52627-2
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