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The autophagic protein LC3 translocates to the nucleus and localizes in the nucleolus associated to NUFIP1 in response to cyclic mechanical stress

The trabecular meshwork (TM) is a key regulatory tissue of intraocular pressure (IOP) in the anterior chamber of eye. Dysfunction of the TM causes resistance to outflow of aqueous humor, which in turn leads to elevated IOP, a main risk factor of glaucomatous neurodegeneration. Due to variations in I...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Shim, Myoung Sup, Nettesheim, April, Hirt, Joshua, Liton, Paloma B.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469449/
https://ncbi.nlm.nih.gov/pubmed/31476975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1662584
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