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Cathepsin B Localizes in the Caveolae and Participates in the Proteolytic Cascade in Trabecular Meshwork Cells. Potential New Drug Target for the Treatment of Glaucoma

Extracellular matrix (ECM) deposition in the trabecular meshwork (TM) is one of the hallmarks of glaucoma, a group of human diseases and leading cause of permanent blindness. The molecular mechanisms underlying ECM deposition in the glaucomatous TM are not known, but it is presumed to be a consequen...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Nettesheim, April, Shim, Myoung Sup, Dixon, Angela, Raychaudhuri, Urmimala, Gong, Haiyan, Liton, Paloma B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795952/
https://ncbi.nlm.nih.gov/pubmed/33379277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10010078
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