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Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: Implications for glaucoma pathogenesis

Increasing evidence suggests oxidative damage as a key factor contributing to the failure of the conventional outflow pathway tissue to maintain appropriate levels of intraocular pressure, and thus increase the risk for developing glaucoma, a late-onset disease which is the second leading cause of p...

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Detalhes bibliográficos
Main Authors: Porter, Kristine, Nallathambi, Jeyabalan, Lin, Yizhi, Liton, Paloma B.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627672/
https://ncbi.nlm.nih.gov/pubmed/23360789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23568
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