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Cathepsin B Is Up-Regulated and Mediates Extracellular Matrix Degradation in Trabecular Meshwork Cells Following Phagocytic Challenge

Cells in the trabecular meshwork (TM), a tissue responsible for draining aqueous humor out of the eye, are known to be highly phagocytic. Phagocytic activity in TM cells is thought to play an important role in outflow pathway physiology. However, the molecular mechanisms triggered by phagocytosis in...

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Hlavní autoři: Porter, Kristine, Lin, Yizhi, Liton, Paloma B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700899/
https://ncbi.nlm.nih.gov/pubmed/23844232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068668
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