Animal Models for Fibrotic Liver Diseases: What We Have, What We Need, and What Is under Development

par Delire, Bénédicte, Stärkel, Peter, Leclercq, Isabelle
Publié dans J Clin Transl Hepatol (2015)

Rationale of adding muscle volume to muscle fat infiltration in the definition of an adverse muscle composition is unclear

par Nachit, Maxime, Horsmans, Yves, Leclercq, Isabelle
Publié dans JHEP Rep (2021)

Why and How Meet n-3 PUFA Dietary Recommendations?

par Molendi-Coste, Olivier, Legry, Vanessa, Leclercq, Isabelle A.
Publié 2011

Role of ciliary dysfunction in a new model of obesity and non-alcoholic steatohepatitis: the foz/foz mice

par Poekes, Laurence, Legry, Vanessa, Farrell, Geoffrey, Leclercq, Isabelle
Publié 2014

Liver Regeneration: Different Sub-Populations of Parenchymal Cells at Play Choreographed by an Injury-Specific Microenvironment

par Manco, Rita, Leclercq, Isabelle A., Clerbaux, Laure-Alix
Publié dans Int J Mol Sci (2018)

Next generation of ALDH substrates and their potential to study maturational lineage biology in stem and progenitor cells

par Dollé, Laurent, Boulter, Luke, Leclercq, Isabelle A., van Grunsven, Leo A.
Publié dans Am J Physiol Gastrointest Liver Physiol (2015)

Chronic liver injury promotes hepatocarcinoma cell seeding and growth, associated with infiltration by macrophages

par Delire, Bénédicte, Henriet, Patrick, Lemoine, Pascale, Leclercq, Isabelle A., Stärkel, Peter
Publié dans Cancer Sci (2018)

Disrupted NF-κB activation after partial hepatectomy does not impair hepatocyte proliferation in rats

par Laurent, Stéphanie, Horsmans, Yves, Stärkel, Peter, Leclercq, Isabelle, Sempoux, Christine, Lambotte, Luc
Publié dans World J Gastroenterol (2005)

Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition

par Charette, Nicolas, De Saeger, Christine, Lannoy, Valérie, Horsmans, Yves, Leclercq, Isabelle, Stärkel, Peter
Publié 2010

Aging enhances liver fibrotic response in mice through hampering extracellular matrix remodeling

par Delire, Bénédicte, Lebrun, Valérie, Selvais, Charlotte, Henriet, Patrick, Bertrand, Amélie, Horsmans, Yves, Leclercq, Isabelle A.
Publié dans Aging (Albany NY) (2016)

The role of pro- and anti-inflammatory responses in silica-induced lung fibrosis

par Barbarin, Virginie, Nihoul, Aurélie, Misson, Pierre, Arras, Mohammed, Delos, Monique, Leclercq, Isabelle, Lison, Dominique, Huaux, Francois
Publié 2005

Kupffer Cells Influence Parenchymal Invasion and Phenotypic Orientation, but Not the Proliferation, of Liver Progenitor Cells in a Murine Model of Liver Injury

par Van Hul, Noémi, Lanthier, Nicolas, Español Suñer, Regina, Abarca Quinones, Jorge, van Rooijen, Nico, Leclercq, Isabelle
Publié 2011

Tumoral response and tumoral phenotypic changes in a rat model of diethylnitrosamine-induced hepatocellular carcinoma after salirasib and sorafenib administration

par Ciccarelli, Olga, Colson, Arthur, De Saeger, Christine, Reding, Raymond, Sempoux, Christine, Leclercq, Isabelle A, Stärkel, Peter
Publié dans Onco Targets Ther (2018)

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

par Leclercq, Isabelle A., Farrell, Geoffrey C., Field, Jaqueline, Bell, David R., Gonzalez, Frank J., Robertson, Graham R.
Publié 2000

Sinusoidal obstruction syndrome (SOS) related to chemotherapy for colorectal liver metastases: factors predictive of severe SOS lesions and protective effect of bevacizumab

par Hubert, Catherine, Sempoux, Christine, Humblet, Yves, van den Eynde, Marc, Zech, Francis, Leclercq, Isabelle, Gigot, Jean-François
Publié dans HPB (Oxford) (2013)

Digital Image Analysis of Picrosirius Red Staining: A Robust Method for Multi-Organ Fibrosis Quantification and Characterization

par Courtoy, Guillaume E., Leclercq, Isabelle, Froidure, Antoine, Schiano, Guglielmo, Morelle, Johann, Devuyst, Olivier, Huaux, François, Bouzin, Caroline
Publié dans Biomolecules (2020)

New insights in acetaminophen toxicity: HMGB1 contributes by itself to amplify hepatocyte necrosis in vitro through the TLR4-TRIF-RIPK3 axis

par Minsart, Charlotte, Liefferinckx, Claire, Lemmers, Arnaud, Dressen, Cindy, Quertinmont, Eric, Leclercq, Isabelle, Devière, Jacques, Moreau, Richard, Gustot, Thierry
Publié dans Sci Rep (2020)

KUPFFER CELLS MEDIATE LEPTIN-INDUCED LIVER FIBROSIS

par Wang, Jianhua, Leclercq, Isabelle, Brymora, Joanne M., Xu, Ning, Ramezani-Moghadam, Mehdi, London, Roslyn M., Brigstock, David, George, Jacob
Publié 2009

Exploiting the biological effect exerted by lipid nanocapsules in non-alcoholic fatty liver disease

par Domingues, Inês, Michalowski, Cecilia Bohns, Marotti, Valentina, Zhang, Wunan, Van Hul, Matthias, Cani, Patrice D., Leclercq, Isabelle A., Beloqui, Ana
Publié dans J Control Release (2023)

Myosteatosis rather than sarcopenia associates with non‐alcoholic steatohepatitis in non‐alcoholic fatty liver disease preclinical models

par Nachit, Maxime, De Rudder, Maxime, Thissen, Jean‐Paul, Schakman, Olivier, Bouzin, Caroline, Horsmans, Yves, Vande Velde, Greetje, Leclercq, Isabelle Anne
Publié dans J Cachexia Sarcopenia Muscle (2020)