Animal Models for Fibrotic Liver Diseases: What We Have, What We Need, and What Is under Development

Por Delire, Bénédicte, Stärkel, Peter, Leclercq, Isabelle
Publicado no J Clin Transl Hepatol (2015)

Rationale of adding muscle volume to muscle fat infiltration in the definition of an adverse muscle composition is unclear

Por Nachit, Maxime, Horsmans, Yves, Leclercq, Isabelle
Publicado no JHEP Rep (2021)

Why and How Meet n-3 PUFA Dietary Recommendations?

Por Molendi-Coste, Olivier, Legry, Vanessa, Leclercq, Isabelle A.
Publicado em 2011

Role of ciliary dysfunction in a new model of obesity and non-alcoholic steatohepatitis: the foz/foz mice

Por Poekes, Laurence, Legry, Vanessa, Farrell, Geoffrey, Leclercq, Isabelle
Publicado em 2014

Liver Regeneration: Different Sub-Populations of Parenchymal Cells at Play Choreographed by an Injury-Specific Microenvironment

Por Manco, Rita, Leclercq, Isabelle A., Clerbaux, Laure-Alix
Publicado no Int J Mol Sci (2018)

Next generation of ALDH substrates and their potential to study maturational lineage biology in stem and progenitor cells

Por Dollé, Laurent, Boulter, Luke, Leclercq, Isabelle A., van Grunsven, Leo A.
Publicado no Am J Physiol Gastrointest Liver Physiol (2015)

Chronic liver injury promotes hepatocarcinoma cell seeding and growth, associated with infiltration by macrophages

Por Delire, Bénédicte, Henriet, Patrick, Lemoine, Pascale, Leclercq, Isabelle A., Stärkel, Peter
Publicado no Cancer Sci (2018)

Disrupted NF-κB activation after partial hepatectomy does not impair hepatocyte proliferation in rats

Por Laurent, Stéphanie, Horsmans, Yves, Stärkel, Peter, Leclercq, Isabelle, Sempoux, Christine, Lambotte, Luc
Publicado no World J Gastroenterol (2005)

Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition

Por Charette, Nicolas, De Saeger, Christine, Lannoy, Valérie, Horsmans, Yves, Leclercq, Isabelle, Stärkel, Peter
Publicado em 2010

Aging enhances liver fibrotic response in mice through hampering extracellular matrix remodeling

Por Delire, Bénédicte, Lebrun, Valérie, Selvais, Charlotte, Henriet, Patrick, Bertrand, Amélie, Horsmans, Yves, Leclercq, Isabelle A.
Publicado no Aging (Albany NY) (2016)

The role of pro- and anti-inflammatory responses in silica-induced lung fibrosis

Por Barbarin, Virginie, Nihoul, Aurélie, Misson, Pierre, Arras, Mohammed, Delos, Monique, Leclercq, Isabelle, Lison, Dominique, Huaux, Francois
Publicado em 2005

Kupffer Cells Influence Parenchymal Invasion and Phenotypic Orientation, but Not the Proliferation, of Liver Progenitor Cells in a Murine Model of Liver Injury

Por Van Hul, Noémi, Lanthier, Nicolas, Español Suñer, Regina, Abarca Quinones, Jorge, van Rooijen, Nico, Leclercq, Isabelle
Publicado em 2011

Tumoral response and tumoral phenotypic changes in a rat model of diethylnitrosamine-induced hepatocellular carcinoma after salirasib and sorafenib administration

Por Ciccarelli, Olga, Colson, Arthur, De Saeger, Christine, Reding, Raymond, Sempoux, Christine, Leclercq, Isabelle A, Stärkel, Peter
Publicado no Onco Targets Ther (2018)

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

Por Leclercq, Isabelle A., Farrell, Geoffrey C., Field, Jaqueline, Bell, David R., Gonzalez, Frank J., Robertson, Graham R.
Publicado em 2000

Sinusoidal obstruction syndrome (SOS) related to chemotherapy for colorectal liver metastases: factors predictive of severe SOS lesions and protective effect of bevacizumab

Por Hubert, Catherine, Sempoux, Christine, Humblet, Yves, van den Eynde, Marc, Zech, Francis, Leclercq, Isabelle, Gigot, Jean-François
Publicado no HPB (Oxford) (2013)

Digital Image Analysis of Picrosirius Red Staining: A Robust Method for Multi-Organ Fibrosis Quantification and Characterization

Por Courtoy, Guillaume E., Leclercq, Isabelle, Froidure, Antoine, Schiano, Guglielmo, Morelle, Johann, Devuyst, Olivier, Huaux, François, Bouzin, Caroline
Publicado no Biomolecules (2020)

New insights in acetaminophen toxicity: HMGB1 contributes by itself to amplify hepatocyte necrosis in vitro through the TLR4-TRIF-RIPK3 axis

Por Minsart, Charlotte, Liefferinckx, Claire, Lemmers, Arnaud, Dressen, Cindy, Quertinmont, Eric, Leclercq, Isabelle, Devière, Jacques, Moreau, Richard, Gustot, Thierry
Publicado no Sci Rep (2020)

KUPFFER CELLS MEDIATE LEPTIN-INDUCED LIVER FIBROSIS

Por Wang, Jianhua, Leclercq, Isabelle, Brymora, Joanne M., Xu, Ning, Ramezani-Moghadam, Mehdi, London, Roslyn M., Brigstock, David, George, Jacob
Publicado em 2009

Exploiting the biological effect exerted by lipid nanocapsules in non-alcoholic fatty liver disease

Por Domingues, Inês, Michalowski, Cecilia Bohns, Marotti, Valentina, Zhang, Wunan, Van Hul, Matthias, Cani, Patrice D., Leclercq, Isabelle A., Beloqui, Ana
Publicado no J Control Release (2023)

Myosteatosis rather than sarcopenia associates with non‐alcoholic steatohepatitis in non‐alcoholic fatty liver disease preclinical models

Por Nachit, Maxime, De Rudder, Maxime, Thissen, Jean‐Paul, Schakman, Olivier, Bouzin, Caroline, Horsmans, Yves, Vande Velde, Greetje, Leclercq, Isabelle Anne
Publicado no J Cachexia Sarcopenia Muscle (2020)