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CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis (NASH) and alcoholic liver disease have similar pathological features. Because CYP2E1 plays a key role in alcoholic liver disease with its ability to stimulate lipid peroxidation, we tested the proposal that CYP2E1 could also be a factor in the development of NASH. In a...

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Detalhes bibliográficos
Main Authors: Leclercq, Isabelle A., Farrell, Geoffrey C., Field, Jaqueline, Bell, David R., Gonzalez, Frank J., Robertson, Graham R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC300833/
https://ncbi.nlm.nih.gov/pubmed/10772651
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