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Aging enhances liver fibrotic response in mice through hampering extracellular matrix remodeling
Clinical data identify age as a factor for severe liver fibrosis. We evaluate whether and how aging modulates the fibrotic response in a mouse model. Liver fibrosis was induced by CCl(4) injections (thrice weekly for 2 weeks) in 7 weeks- and 15 months-old mice (young and old, respectively). Livers w...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5310658/ https://ncbi.nlm.nih.gov/pubmed/27941216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101124 |
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