Smad proteins regulate transcriptional induction of the SM22α gene by TGF-β

Por Chen, Shiyou, Kulik, Magdalena, Lechleider, Robert J.
Publicado em 2003

Thrombotic Microangiopathy with Targeted Cancer Agents

Por Blake-Haskins, John A., Lechleider, Robert J., Kreitman, Robert J.
Publicado em 2011

Transforming Growth Factor-β1 Effects on Endothelial Monolayer Permeability Involve Focal Adhesion Kinase/Src

Por Lee, Young H., Kayyali, Usamah S., Sousa, Anne Marie, Rajan, Thomas, Lechleider, Robert J., Day, Regina M.
Publicado em 2007

SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor β

Por Vindevoghel, Laurence, Lechleider, Robert J., Kon, Atsushi, de Caestecker, Mark P., Uitto, Jouni, Roberts, Anita B., Mauviel, Alain
Publicado em 1998

RhoA Modulates Smad Signaling during Transforming Growth Factor-β-induced Smooth Muscle Differentiation

Por Chen, Shiyou, Crawford, Michelle, Day, Regina M., Briones, Victorino R., Leader, Jennifer E., Jose, Pedro A., Lechleider, Robert J.
Publicado em 2005

A Phase I trial of MGD006 in patients with relapsed acute myeloid leukemia (AML)

Por Uy, Geoffrey, Stewart, Stanford, Baughman, Jan, Rettig, Michael, Chichili, Gurunadh, Bonvini, Ezio, Wigginton, Jon, Lechleider, Robert, DiPersio, John
Publicado no J Immunother Cancer (2014)

Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases

Por de Caestecker, Mark P., Parks, W. Tony, Frank, Chistopher J., Castagnino, Paola, Bottaro, Donald P., Roberts, Anita B., Lechleider, Robert J.
Publicado em 1998

Phase 1, open-label study of MEDI-547 in patients with relapsed or refractory solid tumors

Por Annunziata, Christina M., Kohn, Elise C., LoRusso, Patricia, Houston, Nicole D., Coleman, Robert L., Buzoianu, Manuela, Robbie, Gabriel, Lechleider, Robert
Publicado em 2012

Phase I Trial of Anti-CD22 Recombinant Immunotoxin Moxetumomab Pasudotox (CAT-8015 or HA22) in Patients With Hairy Cell Leukemia

Por Kreitman, Robert J., Tallman, Martin S., Robak, Tadeusz, Coutre, Steven, Wilson, Wyndham H., Stetler-Stevenson, Maryalice, FitzGerald, David J., Lechleider, Robert, Pastan, Ira
Publicado em 2012

Transcriptional activating activity of Smad4: Roles of SMAD hetero-oligomerization and enhancement by an associating transactivator

Por Shioda, Toshi, Lechleider, Robert J., Dunwoodie, Sally L., Li, Huchun, Yahata, Tetsuro, de Caestecker, Mark P., Fenner, Martin H., Roberts, Anita B., Isselbacher, Kurt J.
Publicado em 1998

A novel link between the proteasome pathway and the signal transduction pathway of the Bone Morphogenetic Proteins (BMPs)

Por Lin, Yin, Martin, Jennifer, Gruendler, Cornelia, Farley, Jennifer, Meng, Xianwang, Li, Bi-Yu, Lechleider, Robert, Huff, Carla, Kim, Richard H, Grasser, William, Paralkar, Vishwas, Wang, Tongwen
Publicado em 2002

Safety and Immunologic Response of a Viral Vaccine to PSA in Combination with Radiation Therapy when Metronomic-Dose IL-2 Is Used as an Adjuvant

Por Lechleider, Robert J., Arlen, Philip M., Tsang, Kwong-Yok, Steinberg, Seth M., Yokokawa, Junko, Cereda, Vittore, Camphausen, Kevin, Schlom, Jeffrey, Dahut, William L., Gulley, James L.
Publicado em 2008

A novel Smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-β signal transduction

Por Kim, Richard H., Wang, David, Tsang, Michael, Martin, Jennifer, Huff, Carla, de Caestecker, Mark P., Parks, W. Tony, Meng, Xianwang, Lechleider, Robert J., Wang, Tongwen, Roberts, Anita B.
Publicado em 2000

Circulating Tumor Cells: Application as a Biomarker for Molecular Characterization and Predictor of Survival in an All-Comer Solid Tumor Phase I Clinical Study

Por Bao, Haifeng, Burke, Patricia A., Huang, Jiaqi, Chen, Xiaoru, Brohawn, Philip Z., Yao, Yihong, Lechleider, Robert J., Sikorski, Robert S., Buzoianu, Manuela, Zhang, Jianliang, Shi, Xiaoqing, Richman, Laura K., LaVallee, Theresa M.
Publicado em 2013