Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases

SMAD proteins mediate signals from receptor serine–threonine kinases (RSKs) of the TGF-β superfamily. We demonstrate here that HGF and EGF, which signal through RTKs, can also mediate SMAD-dependent reporter gene activation and induce rapid phosphorylation of endogenous SMAD proteins by kinase(s) do...

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Detalhes bibliográficos
Main Authors: de Caestecker, Mark P., Parks, W. Tony, Frank, Chistopher J., Castagnino, Paola, Bottaro, Donald P., Roberts, Anita B., Lechleider, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC316877/
https://ncbi.nlm.nih.gov/pubmed/9620846
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