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Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases

SMAD proteins mediate signals from receptor serine–threonine kinases (RSKs) of the TGF-β superfamily. We demonstrate here that HGF and EGF, which signal through RTKs, can also mediate SMAD-dependent reporter gene activation and induce rapid phosphorylation of endogenous SMAD proteins by kinase(s) do...

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Kaydedildi:
Yayımlandı:Genes Dev
Asıl Yazarlar: de Caestecker, Mark P., Parks, W. Tony, Frank, Chistopher J., Castagnino, Paola, Bottaro, Donald P., Roberts, Anita B., Lechleider, Robert J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 1998
Konular:
Research Communication
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316877/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9620846/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.11.1587
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