From PIM1 to PI3Kδ via GSK3β: Target Hopping through the Kinome

par Henley, Zoë A., Bax, Benjamin D., Inglesby, Laura M., Champigny, Aurélie, Gaines, Simon, Faulder, Paul, Le, Joelle, Thomas, Daniel A., Washio, Yoshiaki, Baldwin, Ian R.
Publié dans ACS Med Chem Lett (2017)

Structure Activity Relationships of α(v) Integrin Antagonists for Pulmonary Fibrosis by Variation in Aryl Substituents

par Adams, James, Anderson, Edward C., Blackham, Emma E., Chiu, Yin Wa Ryan, Clarke, Thomas, Eccles, Natasha, Gill, Luke A., Haye, Joshua J., Haywood, Harvey T., Hoenig, Christian R., Kausas, Marius, Le, Joelle, Russell, Hannah L., Smedley, Christopher, Tipping, William J., Tongue, Tom, Wood, Charlotte C., Yeung, Jason, Rowedder, James E., Fray, M. Jonathan, McInally, Thomas, Macdonald, Simon J. F.
Publié dans ACS Med Chem Lett (2014)

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

par John, Alison E., Graves, Rebecca H., Pun, K. Tao, Vitulli, Giovanni, Forty, Ellen J., Mercer, Paul F., Morrell, Josie L., Barrett, John W., Rogers, Rebecca F., Hafeji, Maryam, Bibby, Lloyd I., Gower, Elaine, Morrison, Valerie S., Man, Yim, Roper, James A., Luckett, Jeni C., Borthwick, Lee A., Barksby, Ben S., Burgoyne, Rachel A., Barnes, Rory, Le, Joelle, Flint, David J., Pyne, Susan, Habgood, Anthony, Organ, Louise A., Joseph, Chitra, Edwards-Pritchard, Rochelle C., Maher, Toby M., Fisher, Andrew J., Gudmann, Natasja Stæhr, Leeming, Diana J., Chambers, Rachel C., Lukey, Pauline T., Marshall, Richard P., Macdonald, Simon J. F., Jenkins, R. Gisli, Slack, Robert J.
Publié dans Nat Commun (2020)