An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji demethylases

by Upadhyay, Anup K., Rotili, Dante, Han, Ji Woong, Hu, Ruogu, Chang, Yanqi, Labella, Donatella, Zhang, Xing, Yoon, Young-sup, Mai, Antonello, Cheng, Xiaodong
Published 2011

Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies

by Valente, Sergio, Rodriguez, Veronica, Mercurio, Ciro, Vianello, Paola, Saponara, Bruna, Cirilli, Roberto, Ciossani, Giuseppe, Labella, Donatella, Marrocco, Biagina, Ruoppolo, Giovanni, Botrugno, Oronza A., Dessanti, Paola, Minucci, Saverio, Mattevi, Andrea, Varasi, Mario, Mai, Antonello
Published in ACS Med Chem Lett (2014)

New Insights on the Mechanism of Quinoline-based DNA Methyltransferase Inhibitors

by Gros, Christina, Fleury, Laurence, Nahoum, Virginie, Faux, Céline, Valente, Sergio, Labella, Donatella, Cantagrel, Frédéric, Rilova, Elodie, Bouhlel, Mohamed Amine, David-Cordonnier, Marie-Hélène, Dufau, Isabelle, Ausseil, Frédéric, Mai, Antonello, Mourey, Lionel, Lacroix, Laurent, Arimondo, Paola B.
Published in J Biol Chem (2015)

Properly Substituted Analogues of BIX-01294 Lose Inhibition of G9a Histone Methyltransferase and Gain Selective Anti-DNA Methyltransferase 3A Activity

by Rotili, Dante, Tarantino, Domenico, Marrocco, Biagina, Gros, Christina, Masson, Véronique, Poughon, Valérie, Ausseil, Fréderic, Chang, Yanqi, Labella, Donatella, Cosconati, Sandro, Di Maro, Salvatore, Novellino, Ettore, Schnekenburger, Michael, Grandjenette, Cindy, Bouvy, Celine, Diederich, Marc, Cheng, Xiaodong, Arimondo, Paola B., Mai, Antonello
Published 2014

Selective Non-nucleoside Inhibitors of Human DNA Methyltransferases Active in Cancer Including in Cancer Stem Cells

by Valente, Sergio, Liu, Yiwei, Schnekenburger, Michael, Zwergel, Clemens, Cosconati, Sandro, Gros, Christina, Tardugno, Maria, Labella, Donatella, Florean, Cristina, Minden, Steven, Hashimoto, Hideharu, Chang, Yanqi, Zhang, Xing, Kirsch, Gilbert, Novellino, Ettore, Arimondo, Paola B., Miele, Evelina, Ferretti, Elisabetta, Gulino, Alberto, Diederich, Marc, Cheng, Xiaodong, Mai, Antonello
Published 2014