Pathologic and Therapeutic Implications for the Cell Biology of Parkin

ανά Charan, Rakshita A., LaVoie, Matthew J.
Τόπος έκδοσης Mol Cell Neurosci (2015)

Dopamine Quinone Formation and Protein Modification Associated with the Striatal Neurotoxicity of Methamphetamine: Evidence against a Role for Extracellular Dopamine

ανά LaVoie, Matthew J., Hastings, Teresa G.
Τόπος έκδοσης J Neurosci (1999)

Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation

ανά Berger, Zdenek, Smith, Kelsey A., LaVoie, Matthew J.
Έκδοση 2010

The Complex Relationships between Microglia, Alpha-Synuclein, and LRRK2 in Parkinson’s Disease

ανά Schapansky, Jason, Nardozzi, Jonathan D., LaVoie, Matthew J.
Τόπος έκδοσης Neuroscience (2014)

Recognizing the cooperative and independent mitochondrial functions of Parkin and PINK1

ανά Johnson, Bethann N., Charan, Rakshita A., LaVoie, Matthew J.
Έκδοση 2012

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

ανά Ashrafi, Ghazaleh, Schlehe, Julia S., LaVoie, Matthew J., Schwarz, Thomas L.
Έκδοση 2014

Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy

ανά Schapansky, Jason, Nardozzi, Jonathan D., Felizia, Fredrik, LaVoie, Matthew J.
Έκδοση 2014

Proteostasis and Movement Disorders: Parkinson’s Disease and Amyotrophic Lateral Sclerosis

ανά Bosco, Daryl A., LaVoie, Matthew J., Petsko, Gregory A., Ringe, Dagmar
Έκδοση 2011

LRRK2 Kinase Inhibition Rescues Deficits in Lysosome Function Due to Heterozygous GBA1 Expression in Human iPSC-Derived Neurons

ανά Sanyal, Anwesha, Novis, Hailey S., Gasser, Emile, Lin, Steven, LaVoie, Matthew J.
Τόπος έκδοσης Front Neurosci (2020)

The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax

ανά Johnson, Bethann N., Berger, Alison K., Cortese, Giuseppe P., LaVoie, Matthew J.
Έκδοση 2012

Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility

ανά Shlevkov, Evgeny, Kramer, Tal, Schapansky, Jason, LaVoie, Matthew J., Schwarz, Thomas L.
Τόπος έκδοσης Proc Natl Acad Sci U S A (2016)

Genetic deletion of the GATA1-regulated protein α-synuclein reduces oxidative stress and nitric oxide synthase levels in mature erythrocytes

ανά Renella, Raffaele, Schlehe, Julia S., Selkoe, Dennis J., Williams, David A., LaVoie, Matthew J.
Τόπος έκδοσης Am J Hematol (2014)

Aph-1 Associates Directly with Full-length and C-terminal Fragments of γ-Secretase Substrates

ανά Chen, Allen C., Guo, Lucie Y., Ostaszewski, Beth L., Selkoe, Dennis J., LaVoie, Matthew J.
Έκδοση 2010

The mitochondrial disease associated protein Ndufaf2 is dispensable for Complex-1 assembly but critical for the regulation of oxidative stress

ανά Schlehe, Julia S., Journel, Marion S.M., Taylor, Kelsey P., Amodeo, Katherine D., LaVoie, Matthew J.
Έκδοση 2013

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

ανά Kimberly, W. Taylor, LaVoie, Matthew J., Ostaszewski, Beth L., Ye, Wenjuan, Wolfe, Michael S., Selkoe, Dennis J.
Έκδοση 2003

γ-Secretase Substrate Selectivity Can Be Modulated Directly via Interaction with a Nucleotide-binding Site

ανά Fraering, Patrick C., Ye, Wenjuan, LaVoie, Matthew J., Ostaszewski, Beth L., Selkoe, Dennis J., Wolfe, Michael S.
Έκδοση 2005

Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release

ανά Berger, Alison K., Cortese, Giuseppe P., Amodeo, Katherine D., Weihofen, Andreas, Letai, Anthony, LaVoie, Matthew J.
Έκδοση 2009

Lipidomic Profiling in Mouse Brain Reveals Differences Between Ages and Genders, with Smaller Changes Associated with α-Synuclein Genotype

ανά Rappley, Irit, Myers, David S., Milne, Stephen B., Ivanova, Pavlina T., LaVoie, Matthew J., Brown, H. Alex, Selkoe, Dennis J.
Έκδοση 2009

Evidence that α-Synuclein Does Not Inhibit Phospholipase D

ανά Rappley, Irit, Gitler, Aaron D., Selvy, Paige E., LaVoie, Matthew J., Levy, Bruce D., Brown, H. Alex, Lindquist, Susan, Selkoe, Dennis J.
Έκδοση 2009

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

ανά Wang, Xinnan, Winter, Dominic, Ashrafi, Ghazaleh, Schlehe, Julia, Wong, Yao Liang, Selkoe, Dennis, Rice, Sarah, Steen, Judith, LaVoie, Matthew J., Schwarz, Thomas L.
Έκδοση 2011