Lanean...

γ-Secretase Substrate Selectivity Can Be Modulated Directly via Interaction with a Nucleotide-binding Site

γ-Secretase is an unusual protease with an intramembrane catalytic site that cleaves many type I membrane proteins, including the amyloid β-protein (Aβ) precursor (APP) and the Notch receptor. Genetic and biochemical studies have identified four membrane proteins as components of γ-secretase: hetero...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fraering, Patrick C., Ye, Wenjuan, LaVoie, Matthew J., Ostaszewski, Beth L., Selkoe, Dennis J., Wolfe, Michael S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523323/
https://ncbi.nlm.nih.gov/pubmed/16236717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M501368200
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!