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Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial and idiopathic Parkinson's disease. However, the mechanisms for activating its physiological function are not known, hindering identification of the biological role of endogenous LRRK2. The recent discovery...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103671/ https://ncbi.nlm.nih.gov/pubmed/24682598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu138 |
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