Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction

Por Chmelař, Jindřich, Kotál, Jan, Langhansová, Helena, Kotsyfakis, Michail
Publicado no Front Cell Infect Microbiol (2017)

For Whom the Bell Tolls (and Nods): Spit-acular Saliva

Por Shaw, Dana K., Kotsyfakis, Michail, Pedra, Joao H.F.
Publicado no Curr Trop Med Rep (2016)

Anaplasma phagocytophilum: deceptively simple or simply deceptive?

Por Severo, Maiara S, Stephens, Kimberly D, Kotsyfakis, Michail, Pedra, Joao HF
Publicado em 2012

Primary cervical and uterine corpus lymphoma; a case report and literature review

Por Anagnostopoulos, Antonios, Mouzakiti, Niki, Ruthven, Stuart, Herod, Jonathan, Kotsyfakis, Michail
Publicado em 2013

A Nod to disease vectors: mitigation of pathogen sensing by arthropod saliva

Por Sakhon, Olivia S., Severo, Maiara S., Kotsyfakis, Michail, Pedra, Joao H. F.
Publicado em 2013

In silico target network analysis of de novo-discovered, tick saliva-specific microRNAs reveals important combinatorial effects in their interference with vertebrate host physiolog...

Por Hackenberg, Michael, Langenberger, David, Schwarz, Alexandra, Erhart, Jan, Kotsyfakis, Michail
Publicado no RNA (2017)

All for One and One for All on the Tick-Host Battlefield

Por Chmelař, Jindřich, Kotál, Jan, Kopecky, Jan, Pedra, Joao HF, Kotsyfakis, Michail
Publicado no Trends Parasitol (2016)

Tick salivary secretion as a source of antihemostatics

Por Chmelar, Jindrich, Calvo, Eric, Pedra, Joao H.F., Francischetti, Ivo M. B., Kotsyfakis, Michail
Publicado em 2012

<it>Ixodes scapularis</it> saliva mitigates inflammatory cytokine secretion during <it>Anaplasma phagocytophilum</it> stimulation of immune cells

Por Chen Gang, Severo Maiara S, Sohail Mohammad, Sakhon Olivia S, Wikel Stephen K, Kotsyfakis Michail, Pedra Joao HF
Publicado em 2012-10-01

Ixodes scapularis saliva mitigates inflammatory cytokine secretion during Anaplasma phagocytophilum stimulation of immune cells

Por Chen, Gang, Severo, Maiara S, Sohail, Mohammad, Sakhon, Olivia S, Wikel, Stephen K, Kotsyfakis, Michail, Pedra, Joao HF
Publicado em 2012

Simukunin from the Salivary Glands of the Black Fly Simulium vittatum Inhibits Enzymes That Regulate Clotting and Inflammatory Responses

Por Tsujimoto, Hitoshi, Kotsyfakis, Michail, Francischetti, Ivo M. B., Eum, Jai Hoon, Strand, Michael R., Champagne, Donald E.
Publicado em 2012

Sialomes and mialomes: a systems biology view of tick tissues and tick-host interactions

Por Chmelař, Jindřich, Kotál, Jan, Karim, Shahid, Kopacek, Petr, Francischetti, Ivo M.B., Pedra, Joao H.F., Kotsyfakis, Michail
Publicado no Trends Parasitol (2015)

A Systems Level Analysis Reveals Transcriptomic and Proteomic Complexity in Ixodes Ricinus Midgut and Salivary Glands During Early Attachment and Feeding

Por Schwarz, Alexandra, Tenzer, Stefan, Hackenberg, Michael, Erhart, Jan, Gerhold-Ay, Aslihan, Mazur, Johanna, Kuharev, Jörg, Ribeiro, José M. C., Kotsyfakis, Michail
Publicado em 2014

In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus micropl...

Por Assumpção, Teresa C., Ma, Dongying, Mizurini, Daniella M., Kini, R. Manjunatha, Ribeiro, José M. C., Kotsyfakis, Michail, Monteiro, Robson Q., Francischetti, Ivo M. B.
Publicado no PLoS Negl Trop Dis (2016)

An insight into the salivary transcriptome and proteome of the soft tick and vector of epizootic bovine abortion, Ornithodoros coriaceus

Por Francischetti, Ivo M. B., Meng, Zhaojing, Mans, Ben J., Gudderra, Nanda, Hall, Mark, Veenstra, Timothy D., Pham, Van M., Kotsyfakis, Michail, Ribeiro, José M. C.
Publicado em 2008

Modulation of host immunity by tick saliva

Por Kotál, Jan, Langhansová, Helena, Lieskovská, Jaroslava, Andersen, John F., Francischetti, Ivo M.B., Chavakis, Triantafyllos, Kopecký, Jan, Pedra, Joao H. F., Kotsyfakis, Michail, Chmelař, Jindřich
Publicado no J Proteomics (2015)

Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo

Por Ma, Dongying, Mizurini, Daniella M., Assumpção, Teresa C. F., Li, Yuan, Qi, Yanwei, Kotsyfakis, Michail, Ribeiro, José M. C., Monteiro, Robson Q., Francischetti, Ivo M. B.
Publicado em 2013

A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation

Por Chmelar, Jindrich, Oliveira, Carlo J., Rezacova, Pavlina, Francischetti, Ivo M. B., Kovarova, Zuzana, Pejler, Gunnar, Kopacek, Peter, Ribeiro, José M. C., Mares, Michael, Kopecky, Jan, Kotsyfakis, Michail
Publicado em 2011

Alboserpin, a Factor Xa Inhibitor from the Mosquito Vector of Yellow Fever, Binds Heparin and Membrane Phospholipids and Exhibits Antithrombotic Activity

Por Calvo, Eric, Mizurini, Daniella M., Sá-Nunes, Anderson, Ribeiro, José M. C., Andersen, John F., Mans, Ben J., Monteiro, Robson Q., Kotsyfakis, Michail, Francischetti, Ivo M. B.
Publicado em 2011

Anaplasma phagocytophilum Dihydrolipoamide Dehydrogenase 1 Affects Host-Derived Immunopathology during Microbial Colonization

Por Chen, Gang, Severo, Maiara S., Sakhon, Olivia S., Choy, Anthony, Herron, Michael J., Felsheim, Roderick F., Wiryawan, Hilda, Liao, Jiayu, Johns, Jennifer L., Munderloh, Ulrike G., Sutterwala, Fayyaz S., Kotsyfakis, Michail, Pedra, Joao H. F.
Publicado em 2012