Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo

The identity of vampire bat saliva anticoagulant remained elusive for almost a century. Sequencing the salivary gland genes from the vampire bat Desmodus rotundus identified Desmolaris as a novel 21.5-kDa naturally deleted (Kunitz 1-domainless) form of tissue factor pathway inhibitor. Recombinant De...

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Detalhes bibliográficos
Main Authors: Ma, Dongying, Mizurini, Daniella M., Assumpção, Teresa C. F., Li, Yuan, Qi, Yanwei, Kotsyfakis, Michail, Ribeiro, José M. C., Monteiro, Robson Q., Francischetti, Ivo M. B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862280/
https://ncbi.nlm.nih.gov/pubmed/24159172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-517474
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