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Simukunin from the Salivary Glands of the Black Fly Simulium vittatum Inhibits Enzymes That Regulate Clotting and Inflammatory Responses

BACKGROUND: Black flies (Diptera: Simuliidae) feed on blood, and are important vectors of Onchocerca volvulus, the etiolytic agent of River Blindness. Blood feeding depends on pharmacological properties of saliva, including anticoagulation, but the molecules responsible for this activity have not be...

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Main Authors: Tsujimoto, Hitoshi, Kotsyfakis, Michail, Francischetti, Ivo M. B., Eum, Jai Hoon, Strand, Michael R., Champagne, Donald E.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285612/
https://ncbi.nlm.nih.gov/pubmed/22383955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029964
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