In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus

BACKGROUND: Hematophagous mosquitos and ticks avoid host hemostatic system through expression of enzyme inhibitors targeting proteolytic reactions of the coagulation and complement cascades. While most inhibitors characterized to date were found in the salivary glands, relatively few others have bee...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Assumpção, Teresa C., Ma, Dongying, Mizurini, Daniella M., Kini, R. Manjunatha, Ribeiro, José M. C., Kotsyfakis, Michail, Monteiro, Robson Q., Francischetti, Ivo M. B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706430/
https://ncbi.nlm.nih.gov/pubmed/26745503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004298
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