In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus

BACKGROUND: Hematophagous mosquitos and ticks avoid host hemostatic system through expression of enzyme inhibitors targeting proteolytic reactions of the coagulation and complement cascades. While most inhibitors characterized to date were found in the salivary glands, relatively few others have bee...

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Dades bibliogràfiques
Publicat a:PLoS Negl Trop Dis
Autors principals: Assumpção, Teresa C., Ma, Dongying, Mizurini, Daniella M., Kini, R. Manjunatha, Ribeiro, José M. C., Kotsyfakis, Michail, Monteiro, Robson Q., Francischetti, Ivo M. B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706430/
https://ncbi.nlm.nih.gov/pubmed/26745503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004298
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