Application of Rho Kinase Inhibitors for the Treatment of Corneal Endothelial Diseases

door Okumura, Naoki, Kinoshita, Shigeru, Koizumi, Noriko
Gepubliceerd in J Ophthalmol (2017)

Perspective of Future Potent Therapies for Fuchs Endothelial Corneal Dystrophy

door Okumura, Naoki, Hayashi, Ryousuke, Koizumi, Noriko
Gepubliceerd in Open Ophthalmol J (2018)

Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study

door Nakagawa, Hiroko, Koizumi, Noriko, Okumura, Naoki, Suganami, Hideki, Kinoshita, Shigeru
Gepubliceerd in PLoS One (2015)

Myogenic Differentiation from MYOGENIN-Mutated Human iPS Cells by CRISPR/Cas9

door Higashioka, Koki, Koizumi, Noriko, Sakurai, Hidetoshi, Sotozono, Chie, Sato, Takahiko
Gepubliceerd in Stem Cells Int (2017)

Development of Poly Lactic/Glycolic Acid (PLGA) Microspheres for Controlled Release of Rho-Associated Kinase Inhibitor

door Koda, Sho, Okumura, Naoki, Kitano, Junji, Koizumi, Noriko, Tabata, Yasuhiko
Gepubliceerd in J Ophthalmol (2017)

Feasibility of a cryopreservation of cultured human corneal endothelial cells

door Okumura, Naoki, Kagami, Takato, Watanabe, Kyoko, Kadoya, Saori, Sato, Masakazu, Koizumi, Noriko
Gepubliceerd in PLoS One (2019)

Inhibition of TGF-β Signaling Enables Human Corneal Endothelial Cell Expansion In Vitro for Use in Regenerative Medicine

door Okumura, Naoki, Kay, EunDuck P., Nakahara, Makiko, Hamuro, Junji, Kinoshita, Shigeru, Koizumi, Noriko
Gepubliceerd in 2013

Transcriptome dataset of human corneal endothelium based on ribosomal RNA-depleted RNA-Seq data

door Tokuda, Yuichi, Okumura, Naoki, Komori, Yuya, Hanada, Naoya, Tashiro, Kei, Koizumi, Noriko, Nakano, Masakazu
Gepubliceerd in Sci Data (2020)

Density-gradient centrifugation enables the purification of cultured corneal endothelial cells for cell therapy by eliminating senescent cells

door Okumura, Naoki, Kusakabe, Ayaka, Hirano, Hiroatsu, Inoue, Ryota, Okazaki, Yugo, Nakano, Shinichiro, Kinoshita, Shigeru, Koizumi, Noriko
Gepubliceerd in Sci Rep (2015)

Laminin-511 and -521-based matrices for efficient ex vivo-expansion of human limbal epithelial progenitor cells

door Polisetti, Naresh, Sorokin, Lydia, Okumura, Naoki, Koizumi, Noriko, Kinoshita, Shigeru, Kruse, Friedrich E., Schlötzer-Schrehardt, Ursula
Gepubliceerd in Sci Rep (2017)

A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma

door Yamamoto, Mayumi, Quantock, Andrew J., Young, Robert D., Okumura, Naoki, Ueno, Morio, Sakamoto, Yuji, Kinoshita, Shigeru, Koizumi, Noriko
Gepubliceerd in 2012

Corneal Endothelial Expansion Promoted by Human Bone Marrow Mesenchymal Stem Cell-Derived Conditioned Medium

door Nakahara, Makiko, Okumura, Naoki, Kay, EunDuck P., Hagiya, Michio, Imagawa, Kiwamu, Hosoda, Yuuki, Kinoshita, Shigeru, Koizumi, Noriko
Gepubliceerd in 2013

Cultivation of Corneal Endothelial Cells on a Pericellular Matrix Prepared from Human Decidua-Derived Mesenchymal Cells

door Numata, Ryohei, Okumura, Naoki, Nakahara, Makiko, Ueno, Morio, Kinoshita, Shigeru, Kanematsu, Daisuke, Kanemura, Yonehiro, Sasai, Yoshiki, Koizumi, Noriko
Gepubliceerd in 2014

Generation and Feasibility Assessment of a New Vehicle for Cell-Based Therapy for Treating Corneal Endothelial Dysfunction

door Okumura, Naoki, Kakutani, Kazuya, Inoue, Ryota, Matsumoto, Daiki, Shimada, Tomoki, Nakahara, Makiko, Kiyanagi, Yumiko, Itoh, Takehiro, Koizumi, Noriko
Gepubliceerd in PLoS One (2016)

Cultivated oral mucosal epithelial transplantation for persistent epithelial defect in severe ocular surface diseases with acute inflammatory activity

door Sotozono, Chie, Inatomi, Tsutomu, Nakamura, Takahiro, Koizumi, Noriko, Yokoi, Norihiko, Ueta, Mayumi, Matsuyama, Kotone, Kaneda, Hideaki, Fukushima, Masanori, Kinoshita, Shigeru
Gepubliceerd in Acta Ophthalmol (2014)

Ocular Surface Reconstruction With a Tissue-Engineered Nasal Mucosal Epithelial Cell Sheet for the Treatment of Severe Ocular Surface Diseases

door Kobayashi, Masakazu, Nakamura, Takahiro, Yasuda, Makoto, Hata, Yuiko, Okura, Shoki, Iwamoto, Miyu, Nagata, Maho, Fullwood, Nigel J., Koizumi, Noriko, Hisa, Yasuo, Kinoshita, Shigeru
Gepubliceerd in Stem Cells Transl Med (2015)

Feasibility of cell-based therapy combined with descemetorhexis for treating Fuchs endothelial corneal dystrophy in rabbit model

door Okumura, Naoki, Matsumoto, Daiki, Fukui, Yuya, Teramoto, Masataka, Imai, Hirofumi, Kurosawa, Tetta, Shimada, Tomoki, Kruse, Friedrich, Schlötzer-Schrehardt, Ursula, Kinoshita, Shigeru, Koizumi, Noriko
Gepubliceerd in PLoS One (2018)

Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy

door Okumura, Naoki, Hashimoto, Keisuke, Kitahara, Miu, Okuda, Hirokazu, Ueda, Emi, Watanabe, Kyoko, Nakahara, Makiko, Sato, Takahiko, Kinoshita, Shigeru, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich, Koizumi, Noriko
Gepubliceerd in Sci Rep (2017)

Clinical features and management of cytomegalovirus corneal endotheliitis: analysis of 106 cases from the Japan corneal endotheliitis study

door Koizumi, Noriko, Inatomi, Tsutomu, Suzuki, Takashi, Shiraishi, Atsushi, Ohashi, Yuichi, Kandori, Michiko, Miyazaki, Dai, Inoue, Yoshitsugu, Soma, Takeshi, Nishida, Kohji, Takase, Hiroshi, Sugita, Sunao, Mochizuki, Manabu, Kinoshita, Shigeru
Gepubliceerd in Br J Ophthalmol (2015)

A Surgical Cryoprobe for Targeted Transcorneal Freezing and Endothelial Cell Removal

door Akhbanbetova, Alina, Nakano, Shinichiro, Littlechild, Stacy L., Young, Robert D., Zvirgzdina, Madara, Fullwood, Nigel J., Weston, Ian, Weston, Philip, Kinoshita, Shigeru, Okumura, Naoki, Koizumi, Noriko, Quantock, Andrew J.
Gepubliceerd in J Ophthalmol (2017)