Application of Rho Kinase Inhibitors for the Treatment of Corneal Endothelial Diseases

di Okumura, Naoki, Kinoshita, Shigeru, Koizumi, Noriko
Pubblicato in J Ophthalmol (2017)

Perspective of Future Potent Therapies for Fuchs Endothelial Corneal Dystrophy

di Okumura, Naoki, Hayashi, Ryousuke, Koizumi, Noriko
Pubblicato in Open Ophthalmol J (2018)

Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study

di Nakagawa, Hiroko, Koizumi, Noriko, Okumura, Naoki, Suganami, Hideki, Kinoshita, Shigeru
Pubblicato in PLoS One (2015)

Myogenic Differentiation from MYOGENIN-Mutated Human iPS Cells by CRISPR/Cas9

di Higashioka, Koki, Koizumi, Noriko, Sakurai, Hidetoshi, Sotozono, Chie, Sato, Takahiko
Pubblicato in Stem Cells Int (2017)

Development of Poly Lactic/Glycolic Acid (PLGA) Microspheres for Controlled Release of Rho-Associated Kinase Inhibitor

di Koda, Sho, Okumura, Naoki, Kitano, Junji, Koizumi, Noriko, Tabata, Yasuhiko
Pubblicato in J Ophthalmol (2017)

Feasibility of a cryopreservation of cultured human corneal endothelial cells

di Okumura, Naoki, Kagami, Takato, Watanabe, Kyoko, Kadoya, Saori, Sato, Masakazu, Koizumi, Noriko
Pubblicato in PLoS One (2019)

Inhibition of TGF-β Signaling Enables Human Corneal Endothelial Cell Expansion In Vitro for Use in Regenerative Medicine

di Okumura, Naoki, Kay, EunDuck P., Nakahara, Makiko, Hamuro, Junji, Kinoshita, Shigeru, Koizumi, Noriko
Pubblicazione 2013

Transcriptome dataset of human corneal endothelium based on ribosomal RNA-depleted RNA-Seq data

di Tokuda, Yuichi, Okumura, Naoki, Komori, Yuya, Hanada, Naoya, Tashiro, Kei, Koizumi, Noriko, Nakano, Masakazu
Pubblicato in Sci Data (2020)

Density-gradient centrifugation enables the purification of cultured corneal endothelial cells for cell therapy by eliminating senescent cells

di Okumura, Naoki, Kusakabe, Ayaka, Hirano, Hiroatsu, Inoue, Ryota, Okazaki, Yugo, Nakano, Shinichiro, Kinoshita, Shigeru, Koizumi, Noriko
Pubblicato in Sci Rep (2015)

Laminin-511 and -521-based matrices for efficient ex vivo-expansion of human limbal epithelial progenitor cells

di Polisetti, Naresh, Sorokin, Lydia, Okumura, Naoki, Koizumi, Noriko, Kinoshita, Shigeru, Kruse, Friedrich E., Schlötzer-Schrehardt, Ursula
Pubblicato in Sci Rep (2017)

A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma

di Yamamoto, Mayumi, Quantock, Andrew J., Young, Robert D., Okumura, Naoki, Ueno, Morio, Sakamoto, Yuji, Kinoshita, Shigeru, Koizumi, Noriko
Pubblicazione 2012

Corneal Endothelial Expansion Promoted by Human Bone Marrow Mesenchymal Stem Cell-Derived Conditioned Medium

di Nakahara, Makiko, Okumura, Naoki, Kay, EunDuck P., Hagiya, Michio, Imagawa, Kiwamu, Hosoda, Yuuki, Kinoshita, Shigeru, Koizumi, Noriko
Pubblicazione 2013

Cultivation of Corneal Endothelial Cells on a Pericellular Matrix Prepared from Human Decidua-Derived Mesenchymal Cells

di Numata, Ryohei, Okumura, Naoki, Nakahara, Makiko, Ueno, Morio, Kinoshita, Shigeru, Kanematsu, Daisuke, Kanemura, Yonehiro, Sasai, Yoshiki, Koizumi, Noriko
Pubblicazione 2014

Generation and Feasibility Assessment of a New Vehicle for Cell-Based Therapy for Treating Corneal Endothelial Dysfunction

di Okumura, Naoki, Kakutani, Kazuya, Inoue, Ryota, Matsumoto, Daiki, Shimada, Tomoki, Nakahara, Makiko, Kiyanagi, Yumiko, Itoh, Takehiro, Koizumi, Noriko
Pubblicato in PLoS One (2016)

Cultivated oral mucosal epithelial transplantation for persistent epithelial defect in severe ocular surface diseases with acute inflammatory activity

di Sotozono, Chie, Inatomi, Tsutomu, Nakamura, Takahiro, Koizumi, Noriko, Yokoi, Norihiko, Ueta, Mayumi, Matsuyama, Kotone, Kaneda, Hideaki, Fukushima, Masanori, Kinoshita, Shigeru
Pubblicato in Acta Ophthalmol (2014)

Ocular Surface Reconstruction With a Tissue-Engineered Nasal Mucosal Epithelial Cell Sheet for the Treatment of Severe Ocular Surface Diseases

di Kobayashi, Masakazu, Nakamura, Takahiro, Yasuda, Makoto, Hata, Yuiko, Okura, Shoki, Iwamoto, Miyu, Nagata, Maho, Fullwood, Nigel J., Koizumi, Noriko, Hisa, Yasuo, Kinoshita, Shigeru
Pubblicato in Stem Cells Transl Med (2015)

Feasibility of cell-based therapy combined with descemetorhexis for treating Fuchs endothelial corneal dystrophy in rabbit model

di Okumura, Naoki, Matsumoto, Daiki, Fukui, Yuya, Teramoto, Masataka, Imai, Hirofumi, Kurosawa, Tetta, Shimada, Tomoki, Kruse, Friedrich, Schlötzer-Schrehardt, Ursula, Kinoshita, Shigeru, Koizumi, Noriko
Pubblicato in PLoS One (2018)

Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy

di Okumura, Naoki, Hashimoto, Keisuke, Kitahara, Miu, Okuda, Hirokazu, Ueda, Emi, Watanabe, Kyoko, Nakahara, Makiko, Sato, Takahiko, Kinoshita, Shigeru, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich, Koizumi, Noriko
Pubblicato in Sci Rep (2017)

Clinical features and management of cytomegalovirus corneal endotheliitis: analysis of 106 cases from the Japan corneal endotheliitis study

di Koizumi, Noriko, Inatomi, Tsutomu, Suzuki, Takashi, Shiraishi, Atsushi, Ohashi, Yuichi, Kandori, Michiko, Miyazaki, Dai, Inoue, Yoshitsugu, Soma, Takeshi, Nishida, Kohji, Takase, Hiroshi, Sugita, Sunao, Mochizuki, Manabu, Kinoshita, Shigeru
Pubblicato in Br J Ophthalmol (2015)

A Surgical Cryoprobe for Targeted Transcorneal Freezing and Endothelial Cell Removal

di Akhbanbetova, Alina, Nakano, Shinichiro, Littlechild, Stacy L., Young, Robert D., Zvirgzdina, Madara, Fullwood, Nigel J., Weston, Ian, Weston, Philip, Kinoshita, Shigeru, Okumura, Naoki, Koizumi, Noriko, Quantock, Andrew J.
Pubblicato in J Ophthalmol (2017)