Application of Rho Kinase Inhibitors for the Treatment of Corneal Endothelial Diseases

von Okumura, Naoki, Kinoshita, Shigeru, Koizumi, Noriko
Veröffentlicht in J Ophthalmol (2017)

Perspective of Future Potent Therapies for Fuchs Endothelial Corneal Dystrophy

von Okumura, Naoki, Hayashi, Ryousuke, Koizumi, Noriko
Veröffentlicht in Open Ophthalmol J (2018)

Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study

von Nakagawa, Hiroko, Koizumi, Noriko, Okumura, Naoki, Suganami, Hideki, Kinoshita, Shigeru
Veröffentlicht in PLoS One (2015)

Myogenic Differentiation from MYOGENIN-Mutated Human iPS Cells by CRISPR/Cas9

von Higashioka, Koki, Koizumi, Noriko, Sakurai, Hidetoshi, Sotozono, Chie, Sato, Takahiko
Veröffentlicht in Stem Cells Int (2017)

Development of Poly Lactic/Glycolic Acid (PLGA) Microspheres for Controlled Release of Rho-Associated Kinase Inhibitor

von Koda, Sho, Okumura, Naoki, Kitano, Junji, Koizumi, Noriko, Tabata, Yasuhiko
Veröffentlicht in J Ophthalmol (2017)

Feasibility of a cryopreservation of cultured human corneal endothelial cells

von Okumura, Naoki, Kagami, Takato, Watanabe, Kyoko, Kadoya, Saori, Sato, Masakazu, Koizumi, Noriko
Veröffentlicht in PLoS One (2019)

Inhibition of TGF-β Signaling Enables Human Corneal Endothelial Cell Expansion In Vitro for Use in Regenerative Medicine

von Okumura, Naoki, Kay, EunDuck P., Nakahara, Makiko, Hamuro, Junji, Kinoshita, Shigeru, Koizumi, Noriko
Veröffentlicht 2013

Transcriptome dataset of human corneal endothelium based on ribosomal RNA-depleted RNA-Seq data

von Tokuda, Yuichi, Okumura, Naoki, Komori, Yuya, Hanada, Naoya, Tashiro, Kei, Koizumi, Noriko, Nakano, Masakazu
Veröffentlicht in Sci Data (2020)

Density-gradient centrifugation enables the purification of cultured corneal endothelial cells for cell therapy by eliminating senescent cells

von Okumura, Naoki, Kusakabe, Ayaka, Hirano, Hiroatsu, Inoue, Ryota, Okazaki, Yugo, Nakano, Shinichiro, Kinoshita, Shigeru, Koizumi, Noriko
Veröffentlicht in Sci Rep (2015)

Laminin-511 and -521-based matrices for efficient ex vivo-expansion of human limbal epithelial progenitor cells

von Polisetti, Naresh, Sorokin, Lydia, Okumura, Naoki, Koizumi, Noriko, Kinoshita, Shigeru, Kruse, Friedrich E., Schlötzer-Schrehardt, Ursula
Veröffentlicht in Sci Rep (2017)

A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma

von Yamamoto, Mayumi, Quantock, Andrew J., Young, Robert D., Okumura, Naoki, Ueno, Morio, Sakamoto, Yuji, Kinoshita, Shigeru, Koizumi, Noriko
Veröffentlicht 2012

Corneal Endothelial Expansion Promoted by Human Bone Marrow Mesenchymal Stem Cell-Derived Conditioned Medium

von Nakahara, Makiko, Okumura, Naoki, Kay, EunDuck P., Hagiya, Michio, Imagawa, Kiwamu, Hosoda, Yuuki, Kinoshita, Shigeru, Koizumi, Noriko
Veröffentlicht 2013

Cultivation of Corneal Endothelial Cells on a Pericellular Matrix Prepared from Human Decidua-Derived Mesenchymal Cells

von Numata, Ryohei, Okumura, Naoki, Nakahara, Makiko, Ueno, Morio, Kinoshita, Shigeru, Kanematsu, Daisuke, Kanemura, Yonehiro, Sasai, Yoshiki, Koizumi, Noriko
Veröffentlicht 2014

Generation and Feasibility Assessment of a New Vehicle for Cell-Based Therapy for Treating Corneal Endothelial Dysfunction

von Okumura, Naoki, Kakutani, Kazuya, Inoue, Ryota, Matsumoto, Daiki, Shimada, Tomoki, Nakahara, Makiko, Kiyanagi, Yumiko, Itoh, Takehiro, Koizumi, Noriko
Veröffentlicht in PLoS One (2016)

Cultivated oral mucosal epithelial transplantation for persistent epithelial defect in severe ocular surface diseases with acute inflammatory activity

von Sotozono, Chie, Inatomi, Tsutomu, Nakamura, Takahiro, Koizumi, Noriko, Yokoi, Norihiko, Ueta, Mayumi, Matsuyama, Kotone, Kaneda, Hideaki, Fukushima, Masanori, Kinoshita, Shigeru
Veröffentlicht in Acta Ophthalmol (2014)

Ocular Surface Reconstruction With a Tissue-Engineered Nasal Mucosal Epithelial Cell Sheet for the Treatment of Severe Ocular Surface Diseases

von Kobayashi, Masakazu, Nakamura, Takahiro, Yasuda, Makoto, Hata, Yuiko, Okura, Shoki, Iwamoto, Miyu, Nagata, Maho, Fullwood, Nigel J., Koizumi, Noriko, Hisa, Yasuo, Kinoshita, Shigeru
Veröffentlicht in Stem Cells Transl Med (2015)

Feasibility of cell-based therapy combined with descemetorhexis for treating Fuchs endothelial corneal dystrophy in rabbit model

von Okumura, Naoki, Matsumoto, Daiki, Fukui, Yuya, Teramoto, Masataka, Imai, Hirofumi, Kurosawa, Tetta, Shimada, Tomoki, Kruse, Friedrich, Schlötzer-Schrehardt, Ursula, Kinoshita, Shigeru, Koizumi, Noriko
Veröffentlicht in PLoS One (2018)

Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy

von Okumura, Naoki, Hashimoto, Keisuke, Kitahara, Miu, Okuda, Hirokazu, Ueda, Emi, Watanabe, Kyoko, Nakahara, Makiko, Sato, Takahiko, Kinoshita, Shigeru, Tourtas, Theofilos, Schlötzer-Schrehardt, Ursula, Kruse, Friedrich, Koizumi, Noriko
Veröffentlicht in Sci Rep (2017)

Clinical features and management of cytomegalovirus corneal endotheliitis: analysis of 106 cases from the Japan corneal endotheliitis study

von Koizumi, Noriko, Inatomi, Tsutomu, Suzuki, Takashi, Shiraishi, Atsushi, Ohashi, Yuichi, Kandori, Michiko, Miyazaki, Dai, Inoue, Yoshitsugu, Soma, Takeshi, Nishida, Kohji, Takase, Hiroshi, Sugita, Sunao, Mochizuki, Manabu, Kinoshita, Shigeru
Veröffentlicht in Br J Ophthalmol (2015)

A Surgical Cryoprobe for Targeted Transcorneal Freezing and Endothelial Cell Removal

von Akhbanbetova, Alina, Nakano, Shinichiro, Littlechild, Stacy L., Young, Robert D., Zvirgzdina, Madara, Fullwood, Nigel J., Weston, Ian, Weston, Philip, Kinoshita, Shigeru, Okumura, Naoki, Koizumi, Noriko, Quantock, Andrew J.
Veröffentlicht in J Ophthalmol (2017)