The DNA damage response : implications on cancer formation and treatment

Por Khanna, Kum Kum, Shiloh, Yosef
Publicado em 2009

BRCA1 A-Complex fine tunes repair functions of BRCA1

Por Harris, Janelle L, Khanna, Kum Kum
Publicado em 2011

Peptidyl-prolyl isomerization for cytokinetic abscission: Fold and cut

Por van der Horst, Armando, Khanna, Kum Kum
Publicado em 2012

Mouse models uncap novel roles of SSBs

Por Bain, Amanda L, Shi, Wei, Khanna, Kum Kum
Publicado em 2013

Are estrogen receptor-positive breast cancers in BRCA1 mutation carriers sporadic?

Por Lakhani, Sunil R, Khanna, Kum Kum, Chenevix-Trench, Georgia
Publicado em 2010

Involvement of Exo1b in DNA damage-induced apoptosis

Por Bolderson, Emma, Richard, Derek J., Edelmann, Winfried, Khanna, Kum Kum
Publicado em 2009

MEK5-ERK5 pathway associates with poor survival of breast cancer patients after systemic treatments

Por Miranda, Mariska, Rozali, Esdy, Khanna, Kum Kum, Al-Ejeh, Fares
Publicado no Oncoscience (2015)

ATM mediated phosphorylation of CHD4 contributes to genome maintenance

Por Urquhart, Aaron J, Gatei, Magtouf, Richard, Derek J, Khanna, Kum Kum
Publicado em 2011

The Redox State of SECIS Binding Protein 2 Controls Its Localization and Selenocysteine Incorporation Function

Por Papp, Laura V., Lu, Jun, Striebel, Frank, Kennedy, Derek, Holmgren, Arne, Khanna, Kum Kum
Publicado em 2006

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions

Por Tomimatsu, Nozomi, Mukherjee, Bipasha, Deland, Katherine, Kurimasa, Akihiro, Bolderson, Emma, Khanna, Kum Kum, Burma, Sandeep
Publicado em 2012

INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells

Por Morris, Christelle, Tomimatsu, Nozomi, Richard, Derek J, Cluet, David, Burma, Sandeep, Khanna, Kum Kum, Jalinot, Pierre
Publicado em 2012

Inactivation of ATM/ATR DNA Damage Checkpoint Promotes Androgen Induced Chromosomal Instability in Prostate Epithelial Cells

Por Chiu, Yung-Tuen, Liu, Ji, Tang, Kaidun, Wong, Yong-Chuan, Khanna, Kum Kum, Ling, Ming-Tat
Publicado em 2012

Tumor protein D52 represents a negative regulator of ATM protein levels

Por Chen, Yuyan, Kamili, Alvin, Hardy, Jayne R, Groblewski, Guy E, Khanna, Kum Kum, Byrne, Jennifer A
Publicado em 2013

Integrating Multi-omics Data to Dissect Mechanisms of DNA repair Dysregulation in Breast Cancer

Por Liu, Chao, Rohart, Florian, Simpson, Peter T., Khanna, Kum Kum, Ragan, Mark A., Lê Cao, Kim-Anh
Publicado no Sci Rep (2016)

The metastasis suppressor RARRES3 as an endogenous inhibitor of the immunoproteasome expression in breast cancer cells

Por Anderson, Alison M., Kalimutho, Murugan, Harten, Sarah, Nanayakkara, Devathri M., Khanna, Kum Kum, Ragan, Mark A.
Publicado no Sci Rep (2017)

Complex-based analysis of dysregulated cellular processes in cancer

Por Srihari, Sriganesh, Madhamshettiwar, Piyush B, Song, Sarah, Liu, Chao, Simpson, Peter T, Khanna, Kum Kum, Ragan, Mark A
Publicado no BMC Syst Biol (2014)

SCF-FBXO31 E3 Ligase Targets DNA Replication Factor Cdt1 for Proteolysis in the G(2) Phase of Cell Cycle to Prevent Re-replication

Por Johansson, Pegah, Jeffery, Jessie, Al-Ejeh, Fares, Schulz, Renèe B., Callen, David F., Kumar, Raman, Khanna, Kum Kum
Publicado em 2014

Clinical and Molecular Characterization of a Novel Selenocysteine Insertion Sequence-Binding Protein 2 (SBP2) Gene Mutation (R128X)

Por Di Cosmo, Caterina, McLellan, Neil, Liao, Xiao-Hui, Khanna, Kum Kum, Weiss, Roy E., Papp, Laura, Refetoff, Samuel
Publicado em 2009

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

Por Bolderson, Emma, Tomimatsu, Nozomi, Richard, Derek J., Boucher, Didier, Kumar, Rakesh, Pandita, Tej K., Burma, Sandeep, Khanna, Kum Kum
Publicado em 2010

MUC1-C Oncoprotein Interacts Directly with ATM and Promotes the DNA Damage Response to Ionizing Radiation

Por Huang, Lei, Liao, Xiaodong, Beckett, Michael, Li, Yuan, Khanna, Kum Kum, Wang, Zhugang, Kharbanda, Surender, Weichselbaum, Ralph, Kufe, Donald
Publicado em 2010