Evidence for two independent associations with type 1 diabetes at the 12q13 locus

Por Keene, Keith L., Quinlan, Aaron R., Hou, Xuanlin, Hall, Ira M., Mychaleckyj, Josyf C., Onengut-Gumuscu, Suna, Concannon, Patrick
Publicado em 2011

Fine Mapping and Functional Studies of Risk Variants for Type 1 Diabetes at Chromosome 16p13.13

Por Tomlinson, M. Joseph, Pitsillides, Achilleas, Pickin, Rebecca, Mika, Matthew, Keene, Keith L., Hou, Xuanlin, Mychaleckyj, Josyf, Chen, Wei-Min, Concannon, Patrick, Onengut-Gumuscu, Suna
Publicado no Diabetes (2014)

Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population

Por Leak, Tennille S., Keene, Keith L., Langefeld, Carl D., Gallagher, Carla J., Mychaleckyj, Josyf C., Freedman, Barry I., Bowden, Donald W., Rich, Stephen S., Sale, Michèle M.
Publicado em 2007

Evaluation of a SNP map of 6q24-27 confirms diabetic nephropathy loci and identifies novel associations type 2 diabetes patients enriched with nephropathy from an African American...

Por Leak, Tennille S., Mychaleckyj, Josyf C., Smith, Shelly G., Keene, Keith L., Gordon, Candace J., Hicks, Pamela J., Freedman, Barry I., Bowden, Donald W., Sale, Michèle M.
Publicado em 2008

Association Analysis of the Ephrin-B2 Gene in African-Americans with End-Stage Renal Disease

Por Hicks, Pamela J., Staten, Jennifer L., Palmer, Nicholette D., Langefeld, Carl D., Ziegler, Julie T., Keene, Keith L., Sale, Michele M., Bowden, Donald W., Freedman, Barry I.
Publicado em 2008

Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease

Por Keene, Keith L., Mychaleckyj, Josyf C., Leak, Tennille S., Smith, Shelly G., Perlegas, Peter S., Divers, Jasmin, Langefeld, Carl D., Freedman, Barry I., Bowden, Donald W., Sale, Michèle M.
Publicado em 2008

Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy

Por Leak, Tennille S, Langefeld, Carl D, Keene, Keith L, Gallagher, Carla J, Lu, Lingyi, Mychaleckyj, Josyf C, Rich, Stephen S, Freedman, Barry I, Bowden, Donald W, Sale, Michèle M
Publicado em 2010

Comprehensive evaluation of the Estrogen Receptor Alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American populatio...

Por Keene, Keith L., Mychaleckyj, Josyf C., Smith, Shelly G., Leak, Tennille S., Perlegas, Peter S., Langefeld, Carl D., Herrington, David M., Freedman, Barry I., Rich, Stephen S., Bowden, Donald W., Sale, Michèle M.
Publicado em 2008

Genetic drivers of von Willebrand Factor levels in an ischemic stroke population and association with risk for recurrent stroke

Por Williams, Stephen R, Hsu, Fang-Chi, Keene, Keith L, Chen, Wei-Min, Dzhivhuho, Godfrey, Rowles, Joe L, Southerland, Andrew M, Furie, Karen L, Rich, Stephen S, Worrall, Bradford B, Sale, Michèle M
Publicado no Stroke (2017)

The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family S...

Por Sale, Michèle M, Hsu, Fang-Chi, Palmer, Nicholette D, Gordon, Candace J, Keene, Keith L, Borgerink, Hermina M, Sharma, Arun J, Bergman, Richard N, Taylor, Kent D, Saad, Mohammed F, Norris, Jill M
Publicado em 2007

Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial

Por Keene, Keith L., Chen, Wei-Min, Chen, Fang, Williams, Stephen R., Elkhatib, Stacey D., Hsu, Fang-Chi, Mychaleckyj, Josyf C., Doheny, Kimberly F., Pugh, Elizabeth W., Ling, Hua, Laurie, Cathy C., Gogarten, Stephanie M., Madden, Ebony B., Worrall, Bradford B., Sale, Michele M.
Publicado em 2014

Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of ALDH1L1 with Ischemic Stroke

Por Williams, Stephen R., Yang, Qiong, Chen, Fang, Liu, Xuan, Keene, Keith L., Jacques, Paul, Chen, Wei-Min, Weinstein, Galit, Hsu, Fang-Chi, Beiser, Alexa, Wang, Liewei, Bookman, Ebony, Doheny, Kimberly F., Wolf, Philip A., Zilka, Michelle, Selhub, Jacob, Nelson, Sarah, Gogarten, Stephanie M., Worrall, Bradford B., Seshadri, Sudha, Sale, Michèle M.
Publicado em 2014

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke

Por Williams, Stephen R., Hsu, Fang-Chi, Keene, Keith L., Chen, Wei-Min, Nelson, Sarah, Southerland, Andrew M., Madden, Ebony B., Coull, Bruce, Gogarten, Stephanie M., Furie, Karen L., Dzhivhuho, Godfrey, Rowles, Joe L., Mehndiratta, Prachi, Malik, Rainer, Dupuis, Josée, Lin, Honghuang, Seshadri, Sudha, Rich, Stephen S., Sale, Michèle M., Worrall, Bradford B.
Publicado no Neurology (2016)

Meta-analysis of genome-wide association studies identifies genetic risk factors for stroke in African-Americans

Por Carty, Cara L., Keene, Keith L., Cheng, Yu-Ching, Meschia, James F., Chen, Wei-Min, Nalls, Mike, Bis, Joshua C., Kittner, Steven J., Rich, Stephen S., Tajuddin, Salman, Zonderman, Alan B., Evans, Michele K., Langefeld, Carl D., Gottesman, Rebecca, Mosley, Thomas H., Shahar, Eyal, Woo, Daniel, Yaffe, Kristine, Liu, YongMei, Sale, Michèle M., Dichgans, Martin, Malik, Rainer, Longstreth, WT, Mitchell, Braxton D., Psaty, Bruce M., Kooperberg, Charles, Reiner, Alexander, Worrall, Bradford B., Fornage, Myriam
Publicado no Stroke (2015)

GRECOS project. The use of genetics to predict the vascular recurrence after stroke

Por Fernández-Cadenas, Israel, Mendióroz, Maite, Giralt, Dolors, Nafria, Cristina, Garcia, Elena, Carrera, Caty, Gallego-Fabrega, Cristina, Domingues-Montanari, Sophie, Delgado, Pilar, Ribó, Marc, Castellanos, Mar, Martínez, Sergi, Freijo, Mari Mar, Jiménez-Conde, Jordi, Rubiera, Marta, Alvarez-Sabín, José, Molina, Carlos A., Font, Maria Angels, Olivares, Marta Grau, Palomeras, Ernest, de la Ossa, Natalia Perez, Martinez-Zabaleta, Maite, Masjuan, Jaime, Moniche, Francisco, Canovas, David, Piñana, Carlos, Purroy, Francisco, Cocho, Dolores, Navas, Inma, Tejero, Carlos, Aymerich, Nuria, Cullell, Natalia, Muiño, Elena, Serena, Joaquín, Rubio, Francisco, Davalos, Antoni, Roquer, Jaume, Arenillas, Juan Francisco, Martí-Fábregas, Joan, Keene, Keith, Chen, Wei-Min, Worrall, Bradford, Sale, Michele, Arboix, Adrià, Krupinski, Jerzy, Montaner, Joan
Publicado no Stroke (2017)

Are Myocardial Infarction–Associated Single-Nucleotide Polymorphisms Associated With Ischemic Stroke?

Por Cheng, Yu-Ching, Anderson, Christopher D., Bione, Silvia, Keene, Keith, Maguire, Jane M., Nalls, Michael, Rasheed, Asif, Zeginigg, Marion, Attia, John, Baker, Ross, Barlera, Simona, Biffi, Alessandro, Bookman, Ebony, Brott, Thomas G., Brown, Robert D., Fang Chen, PhD, Chen, Wei-Min, Ciusani, Emilio, Cole, John W., Cortellini, Lynelle, Danesh, John, Doheny, Kimberly, Ferrucci, Luigi, Franzosi, Maria Grazia, Frossard, Philippe, Furie, Karen L., Golledge, Jonathan, Hankey, Graeme J., Hernandez, Dena, Holliday, Elizabeth G., Hsu, Fang-Chi, Jannes, Jim, Kamal, Ayeesha, Khan, Muhammad Saleem, Kittner, Steven J., Koblar, Simon A., Lewis, Martin, Lincz, Lisa, Lisa, Antonella, Matarin, Mar, Moscato, Pablo, Mychaleckyj, Josyf C., Parati, Eugenio A., Parolo, Silvia, Pugh, Elizabeth, Rost, Natalia S., Schallert, Michael, Schmidt, Helena, Scott, Rodney J., Sturm, Jonathan W., Yadav, Sunaina, Zaidi, Moazzam, Boncoraglio, Giorgio B., Levi, Christopher Royce, Meschia, James F., Rosand, Jonathan, Sale, Michele, Saleheen, Danish, Schmidt, Reinhold, Sharma, Pankaj, Worrall, Bradford, Mitchell, Braxton D.
Publicado em 2012

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

Por Ng, Maggie C. Y., Shriner, Daniel, Chen, Brian H., Li, Jiang, Chen, Wei-Min, Guo, Xiuqing, Liu, Jiankang, Bielinski, Suzette J., Yanek, Lisa R., Nalls, Michael A., Comeau, Mary E., Rasmussen-Torvik, Laura J., Jensen, Richard A., Evans, Daniel S., Sun, Yan V., An, Ping, Patel, Sanjay R., Lu, Yingchang, Long, Jirong, Armstrong, Loren L., Wagenknecht, Lynne, Yang, Lingyao, Snively, Beverly M., Palmer, Nicholette D., Mudgal, Poorva, Langefeld, Carl D., Keene, Keith L., Freedman, Barry I., Mychaleckyj, Josyf C., Nayak, Uma, Raffel, Leslie J., Goodarzi, Mark O., Chen, Y-D Ida, Taylor, Herman A., Correa, Adolfo, Sims, Mario, Couper, David, Pankow, James S., Boerwinkle, Eric, Adeyemo, Adebowale, Doumatey, Ayo, Chen, Guanjie, Mathias, Rasika A., Vaidya, Dhananjay, Singleton, Andrew B., Zonderman, Alan B., Igo, Robert P., Sedor, John R., Kabagambe, Edmond K., Siscovick, David S., McKnight, Barbara, Rice, Kenneth, Liu, Yongmei, Hsueh, Wen-Chi, Zhao, Wei, Bielak, Lawrence F., Kraja, Aldi, Province, Michael A., Bottinger, Erwin P., Gottesman, Omri, Cai, Qiuyin, Zheng, Wei, Blot, William J., Lowe, William L., Pacheco, Jennifer A., Crawford, Dana C., Grundberg, Elin, Rich, Stephen S., Hayes, M. Geoffrey, Shu, Xiao-Ou, Loos, Ruth J. F., Borecki, Ingrid B., Peyser, Patricia A., Cummings, Steven R., Psaty, Bruce M., Fornage, Myriam, Iyengar, Sudha K., Evans, Michele K., Becker, Diane M., Kao, W. H. Linda, Wilson, James G., Rotter, Jerome I., Sale, Michèle M., Liu, Simin, Rotimi, Charles N., Bowden, Donald W.
Publicado em 2014

Genome-wide Association Analysis of Blood-Pressure Traits in African-Ancestry Individuals Reveals Common Associated Genes in African and Non-African Populations

Por Franceschini, Nora, Fox, Ervin, Zhang, Zhaogong, Edwards, Todd L., Nalls, Michael A., Sung, Yun Ju, Tayo, Bamidele O., Sun, Yan V., Gottesman, Omri, Adeyemo, Adebawole, Johnson, Andrew D., Young, J. Hunter, Rice, Ken, Duan, Qing, Chen, Fang, Li, Yun, Tang, Hua, Fornage, Myriam, Keene, Keith L., Andrews, Jeanette S., Smith, Jennifer A., Faul, Jessica D., Guangfa, Zhang, Guo, Wei, Liu, Yu, Murray, Sarah S., Musani, Solomon K., Srinivasan, Sathanur, Velez Edwards, Digna R., Wang, Heming, Becker, Lewis C., Bovet, Pascal, Bochud, Murielle, Broeckel, Ulrich, Burnier, Michel, Carty, Cara, Chasman, Daniel I., Ehret, Georg, Chen, Wei-Min, Chen, Guanjie, Chen, Wei, Ding, Jingzhong, Dreisbach, Albert W., Evans, Michele K., Guo, Xiuqing, Garcia, Melissa E., Jensen, Rich, Keller, Margaux F., Lettre, Guillaume, Lotay, Vaneet, Martin, Lisa W., Moore, Jason H., Morrison, Alanna C., Mosley, Thomas H., Ogunniyi, Adesola, Palmas, Walter, Papanicolaou, George, Penman, Alan, Polak, Joseph F., Ridker, Paul M., Salako, Babatunde, Singleton, Andrew B., Shriner, Daniel, Taylor, Kent D., Vasan, Ramachandran, Wiggins, Kerri, Williams, Scott M., Yanek, Lisa R., Zhao, Wei, Zonderman, Alan B., Becker, Diane M., Berenson, Gerald, Boerwinkle, Eric, Bottinger, Erwin, Cushman, Mary, Eaton, Charles, Nyberg, Fredrik, Heiss, Gerardo, Hirschhron, Joel N., Howard, Virginia J., Karczewsk, Konrad J., Lanktree, Matthew B., Liu, Kiang, Liu, Yongmei, Loos, Ruth, Margolis, Karen, Snyder, Michael, Psaty, Bruce M., Schork, Nicholas J., Weir, David R., Rotimi, Charles N., Sale, Michele M., Harris, Tamara, Kardia, Sharon L.R., Hunt, Steven C., Arnett, Donna, Redline, Susan, Cooper, Richard S., Risch, Neil J., Rao, D.C., Rotter, Jerome I., Chakravarti, Aravinda, Reiner, Alex P., Levy, Daniel, Keating, Brendan J., Zhu, Xiaofeng
Publicado em 2013

Genome-Wide Association Study for Circulating Tissue Plasminogen Activator (tPA) Levels and Functional Follow-up Implicates Endothelial STXBP5 and STX2

Por Huang, Jie, Huffman, Jennifer E., Yamkauchi, Munekazu, Trompet, Stella, Asselbergs, Folkert W., Sabater-Lleal, Maria, Trégouët, David-Alexandre, Chen, Wei-Min, Smith, Nicholas L., Kleber, Marcus E., Shin, So-Youn, Becker, Diane M., Tang, Weihong, Dehghan, Abbas, Johnson, Andrew D., Truong, Vinh, Folkersen, Lasse, Yang, Qiong, Oudot-Mellakh, Tiphaine, Buckley, Brendan M., Moore, Jason H., Williams, Frances M.K., Campbell, Harry, Silbernagel, Günther, Vitart, Veronique, Rudan, Igor, Tofler, Geoffrey H., Navis, Gerjan J., DeStefano, Anita, Wright, Alan F., Chen, Ming-Huei, de Craen, Anton J.M., Worrall, Bradford B., Rudnicka, Alicja R., Rumley, Ann, Bookman, Ebony B., Psaty, Bruce M., Chen, Fang, Keene, Keith L., Franco, Oscar H., Böhm, Bernhard O., Uitterlinden, Andre G., Carter, Angela M., Jukema, J. Wouter, Sattar, Naveed, Bis, Joshua C., Ikram, Mohammad A., Sale, Michèle M., McKnight, Barbara, Fornage, Myriam, Ford, Ian, Taylor, Kent, Slagboom, P. Eline, McArdle, Wendy L., Hsu, Fang-Chi, Franco-Cereceda, Anders, Goodall, Alison H., Yanek, Lisa R., Furie, Karen L., Cushman, Mary, Hofman, Albert, Witteman, Jacqueline CM., Folsom, Aaron R., Basu, Saonli, Matijevic, Nena, van Gilst, Wiek H., Wilson, James F., Westendorp, Rudi G.J., Kathiresan, Sekar, Reilly, Muredach P., Tracy, Russell P., Polasek, Ozren, Winkelmann, Bernhard R., Grant, Peter J., Hillege, Hans L., Cambien, Francois, Stott, David J., Lowe, Gordon D., Spector, Timothy D., Meigs, James B., Marz, Winfried, Eriksson, Per, Becker, Lewis C., Morange, Pierre-Emmanuel, Soranzo, Nicole, Williams, Scott M., Hayward, Caroline, van der Harst, Pim, Hamsten, Anders, Lowenstein, Charles J., Strachan, David P., O'Donnell, Christopher J.
Publicado em 2014

The NINDS Stroke Genetics Network: a genome-wide association study of ischemic stroke and its subtypes

Por Pulit, Sara L., McArdle, Patrick F., Wong, Quenna, Malik, Rainer, Gwinn, Katrina, Achterberg, Sefanja, Algra, Ale, Amouyel, Philippe, Anderson, Christopher D., Arnett, Donna K., Arsava, Ethem Murat, Attia, John, Ay, Hakan, Bartz, Traci M., Battey, Thomas, Benavente, Oscar R., Bevan, Steve, Biffi, Alessandro, Bis, Joshua C., Blanton, Susan H., Boncoraglio, Giorgio B., Brown, Robert D., Burgess, Annette I., Carrera, Caty, Chapman Smith, Sherita N., Chasman, Daniel I., Chauhan, Ganesh, Chen, Wei-Min, Cheng, Yu-Ching, Chong, Michael, Cloonan, Lisa K., Cole, John W., Cotlarciuc, Ioana, Cruchaga, Carlos, Cuadrado-Godia, Elisa, Dave, Tushar, Dawson, Jesse, Debette, Stéphanie, Delavaran, Hossein, Dell, Cameron A., Dichgans, Martin, Doheny, Kimberly F., Dong, Chuanhui, Duggan, David J., Engström, Gunnar, Evans, Michele K., Pallejà, Xavier Estivill, Faul, Jessica D., Fernández-Cadenas, Israel, Fornage, Myriam, Frossard, Philippe M., Furie, Karen, Gamble, Dale M., Gieger, Christian, Giese, Anne-Katrin, Giralt-Steinhauer, Eva, González, Hector M., Goris, An, Gretarsdottir, Solveig, Grewal, Raji P., Grittner, Ulrike, Gustafsson, Stefan, Han, Buhm, Hankey, Graeme J., Heitsch, Laura, Higgins, Peter, Hochberg, Marc C., Holliday, Elizabeth, Hopewell, Jemma C., Horenstein, Richard B., Howard, George, Ikram, M. Arfan, Ilinca, Andreea, Ingelsson, Erik, Irvin, Marguerite R., Jackson, Rebecca D., Jern, Christina, Conde, Jordi Jiménez, Johnson, Julie A., Jood, Katarina, Kahn, Muhammad S., Kaplan, Robert, Kappelle, L. Jaap, Kardia, Sharon L.R., Keene, Keith L., Kissela, Brett M., Kleindorfer, Dawn O., Koblar, Simon, Labovitz, Daniel, Launer, Lenore J., Laurie, Cathy C., Laurie, Cecelia A., Lee, Cue Hyunkyu, Lee, Jin-Moo, Lehm, Manuel, Lemmens, Robin, Levi, Christopher, Leys, Didier, Lindgren, Arne, Longstreth, W. T., Maguire, Jane, Manichaikul, Ani, Markus, Hugh S., McClure, Leslie A., McDonough, Caitrin W., Meisinger, Christa, Melander, Olle, Meschia, James F., Mola-Caminal, Marina, Montaner, Joan, Mosley, Thomas H., Müller-Nurasyid, Martina, Nalls, Mike A., O’Connell, Jeffrey R., O’Donnell, Martin, Ois, Ángel, Papanicolaou, George J., Paré, Guillaume, Peddareddygari, Leema Reddy, Pedersén, Annie, Pera, Joanna, Peters, Annette, Poole, Deborah, Psaty, Bruce M., Rabionet, Raquel, Raffeld, Miriam R., Rannikmäe, Kristiina, Rasheed, Asif, Redfors, Petra, Reiner, Alex P., Rexrode, Kathryn, Ribasés, Marta, Rich, Stephen S., Robberecht, Wim, Rodriguez-Campello, Ana, Rolfs, Arndt, Roquer, Jaume, Rose, Lynda M., Rosenbaum, Daniel, Rost, Natalia S., Rothwell, Peter M., Rundek, Tatjana, Ryan, Kathleen A., Sacco, Ralph L., Sale, Michèle M., Saleheen, Danish, Salomaa, Veikko, Sánchez-Mora, Cristina, Schmidt, Carsten Oliver, Schmidt, Helena, Schmidt, Reinhold, Schürks, Markus, Scott, Rodney, Segal, Helen C., Seiler, Stephan, Seshadri, Sudha, Sharma, Pankaj, Shuldiner, Alan R., Silver, Brian, Slowik, Agnieszka, Smith, Jennifer A., Söderholm, Martin, Soriano, Carolina, Sparks, Mary J., Stanne, Tara, Stefansson, Kari, Stine, O. Colin, Strauch, Konstantin, Sturm, Jonathan, Sudlow, Cathie LM, Tajuddin, Salman M., Talbert, Robert L., Tatlisumak, Turgut, Thijs, Vincent, Thorleifsson, Gudmar, Thorsteindottir, Unnur, Tiedt, Steffen, Traylor, Matthew, Trompet, Stella, Valant, Valerie, Waldenberger, Melanie, Walters, Matthew, Wang, Liyong, Wassertheil-Smoller, Sylvia, Weir, David R., Wiggins, Kerri L., Williams, Stephen R., Wloch-Kopec, Dorota, Woo, Daniel, Woodfield, Rebecca, Wu, Ona, Xu, Huichun, Zonderman, Alan B., Worrall, Bradford B., de Bakker, Paul I.W., Kittner, Steven J., Mitchell, Braxton D., Rosand, Jonathan
Publicado no Lancet Neurol (2015)