Update on Gene Therapy for Immunodeficiencies

Por Kohn, Donald B.
Publicado em 2010

Envelope, please. And the award goes to…

Por Kohn, Donald B., Hollis, Roger P.
Publicado em 2014

Gene Therapy for the Treatment of Primary Immune Deficiencies

Por Kuo, Caroline Y., Kohn, Donald B.
Publicado no Curr Allergy Asthma Rep (2016)

New Frontiers in the Therapy of Primary Immunodeficiency: From Gene Addition to Gene Editing

Por Kohn, Donald B., Kuo, Caroline Y.
Publicado no J Allergy Clin Immunol (2017)

Hematopoietic Stem Cells for Cancer Immunotherapy

Por Gschweng, Eric, Oliveira, Satiro De, Kohn, Donald B.
Publicado em 2014

Genetic therapies against HIV

Por Rossi, John J, June, Carl H, Kohn, Donald B
Publicado no Nat Biotechnol (2007)

Hematopoietic Stem Cell Gene Therapy –Progress and Lessons Learned

Por Morgan, Richard A., Gray, David, Lomova, Anastasia, Kohn, Donald B.
Publicado no Cell Stem Cell (2017)

Lentivirus Vectors Incorporating the Immunoglobulin Heavy Chain Enhancer and Matrix Attachment Regions Provide Position-Independent Expression in B Lymphocytes

Por Lutzko, Carolyn, Senadheera, Dinithi, Skelton, Dianne, Petersen, Denise, Kohn, Donald B.
Publicado em 2003

Integrated Self-Inactivating Lentiviral Vectors Produce Full-Length Genomic Transcripts Competent for Encapsidation and Integration

Por Logan, Aaron C., Haas, Dennis L., Kafri, Tal, Kohn, Donald B.
Publicado em 2004

Rescue of splicing-mediated intron loss maximizes expression in lentiviral vectors containing the human ubiquitin C promoter

Por Cooper, Aaron R., Lill, Georgia R., Gschweng, Eric H., Kohn, Donald B.
Publicado no Nucleic Acids Res (2015)

Long-Term Neurocognitive Function of Pediatric Patients with Severe Combined Immune Deficiency (SCID): Pre- and Post-Hematopoietic Stem Cell Transplant (HSCT)

Por Lin, Malinda, Epport, Karen, Azen, Colleen, Parkman, Robertson, Kohn, Donald B., Shah, Ami J.
Publicado no J Clin Immunol (2008)

Integrase-defective Lentiviral Vectors as a Delivery Platform for Targeted Modification of Adenosine Deaminase Locus

Por Joglekar, Alok V, Hollis, Roger P, Kuftinec, Gabriela, Senadheera, Shantha, Chan, Rebecca, Kohn, Donald B
Publicado em 2013

Highly Efficient Large-Scale Lentiviral Vector Concentration by Tandem Tangential Flow Filtration

Por Cooper, Aaron R., Patel, Sanjeet, Senadheera, Shantha, Plath, Kathrin, Kohn, Donald B., Hollis, Roger P.
Publicado no J Virol Methods (2011)

Improving Gene Therapy Efficiency through the Enrichment of Human Hematopoietic Stem Cells

Por Masiuk, Katelyn E., Brown, Devin, Laborada, Jennifer, Hollis, Roger P., Urbinati, Fabrizia, Kohn, Donald B.
Publicado no Mol Ther (2017)

Novel Pol II Fusion Promoter Directs Human Immunodeficiency Virus Type 1-Inducible Coexpression of a Short Hairpin RNA and Protein

Por Unwalla, Hoshang J., Li, Hai-Tang, Bahner, Ingrid, Li, Ming-Jie, Kohn, Donald, Rossi, John J.
Publicado em 2006

Guidance for Developing Phase II Cell Therapy Trial Proposals for Consideration by the Blood and Marrow Transplant Clinical Trials Network

Por Horwitz, Edwin M, Horowitz, Mary M, DiFronzo, Nancy L, Kohn, Donald B, Heslop, Helen E
Publicado em 2010

Hematopoietic Stem Cell Gene Therapy for the Multisystemic Lysosomal Storage Disorder Cystinosis

Por Harrison, Frank, Yeagy, Brian A, Rocca, Celine J, Kohn, Donald B, Salomon, Daniel R, Cherqui, Stephanie
Publicado em 2013

Dissecting the Mechanism of Histone Deacetylase Inhibitors to Enhance the Activity of Zinc Finger Nucleases Delivered by Integrase-Defective Lentiviral Vectors

Por Joglekar, Alok V., Stein, Libby, Ho, Michelle, Hoban, Megan D., Hollis, Roger P., Kohn, Donald B.
Publicado em 2014

PGE2 and Poloxamer Synperonic F108 Enhance Transduction of Human HSPCs with a β-Globin Lentiviral Vector

Por Masiuk, Katelyn E., Zhang, Ruixue, Osborne, Kyle, Hollis, Roger P., Campo-Fernandez, Beatriz, Kohn, Donald B.
Publicado no Mol Ther Methods Clin Dev (2019)

Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells

Por Robbins, Paul B., Skelton, Dianne C., Yu, Xiao-Jin, Halene, Stephanie, Leonard, Earl H., Kohn, Donald B.
Publicado em 1998