EIF4G1 mutations do not cause Parkinson’s disease

Por Nichols, Noah, Bras, Jose M, Hernandez, Dena G, Jansen, Iris E, Lesage, Suzanne, Lubbe, Steven, Singleton, Andrew B
Publicado no Neurobiol Aging (2015)

Excessive burden of lysosomal storage disorder gene variants in Parkinson’s disease

Por Robak, Laurie A, Jansen, Iris E, van Rooij, Jeroen, Uitterlinden, André G, Kraaij, Robert, Jankovic, Joseph, Heutink, Peter, Shulman, Joshua M
Publicado no Brain (2017)

A Twin-Sibling Study on the Relationship Between Exercise Attitudes and Exercise Behavior

Por Huppertz, Charlotte, Bartels, Meike, Jansen, Iris E., Boomsma, Dorret I., Willemsen, Gonneke, de Moor, Marleen H. M., de Geus, Eco J. C.
Publicado em 2013

Comprehensive promoter level expression quantitative trait loci analysis of the human frontal lobe

Por Blauwendraat, Cornelis, Francescatto, Margherita, Gibbs, J. Raphael, Jansen, Iris E., Simón-Sánchez, Javier, Hernandez, Dena G., Dillman, Allissa A., Singleton, Andrew B., Cookson, Mark R., Rizzu, Patrizia, Heutink, Peter
Publicado no Genome Med (2016)

The wide genetic landscape of clinical frontotemporal dementia: systematic combined sequencing of 121 consecutive subjects

Por Blauwendraat, Cornelis, Wilke, Carlo, Simón-Sánchez, Javier, Jansen, Iris E, Reifschneider, Anika, Capell, Anja, Haass, Christian, Castillo-Lizardo, Melissa, Biskup, Saskia, Maetzler, Walter, Rizzu, Patrizia, Heutink, Peter, Synofzik, Matthis
Publicado no Genet Med (2018)

Lack of evidence for a role of genetic variation in TMEM230 in the risk for Parkinson’s disease in the Caucasian population

Por Giri, Anamika, Mok, Kin Y., Jansen, Iris, Sharma, Manu, Tesson, Christelle, Mangone, Graziella, Lesage, Suzanne, Bras, José M., Shulman, Joshua M., Sheerin, Una-Marie, Díez-Fairen, Mónica, Pastor, Pau, Martí, María José, Ezquerra, Mario, Tolosa, Eduardo, Correia-Guedes, Leonor, Ferreira, Joaquim, Amin, Najaf, van Duijn, Cornelia M., van Rooij, Jeroen, Uitterlinden, André G., Kraaij, Robert, Nalls, Michael, Simón-Sánchez, Javier
Publicado no Neurobiol Aging (2016)

Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance

Por Lubbe, Steven J., Escott-Price, Valentina, Gibbs, J. Raphael, Nalls, Mike A., Bras, Jose, Price, T. Ryan, Nicolas, Aude, Jansen, Iris E., Mok, Kin Y., Pittman, Alan M., Tomkins, James E., Lewis, Patrick A., Noyce, Alastair J., Lesage, Suzanne, Sharma, Manu, Schiff, Elena R., Levine, Adam P., Brice, Alexis, Gasser, Thomas, Hardy, John, Heutink, Peter, Wood, Nicholas W., Singleton, Andrew B., Williams, Nigel M., Morris, Huw R.
Publicado no Hum Mol Genet (2016)

Prediction of cognition in Parkinson’s disease with a clinical-genetic score: a longitudinal analysis of nine cohorts

Por Liu, Ganqiang, Locascio, Joseph J., Corvol, Jean-Christophe, Boot, Brendon, Liao, Zhixiang, Page, Kara, Franco, Daly, Burke, Kyle, Jansen, Iris E., Trisini-Lipsanopoulos, Ana, Winder-Rhodes, Sophie, Tanner, Caroline M., Lang, Anthony E., Eberly, Shirley, Elbaz, Alexis, Brice, Alexis, Mangone, Graziella, Ravina, Bernard, Shoulson, Ira, Cormier-Dequaire, Florence, Heutink, Peter, van Hilten, Jacobus J., Barker, Roger A., Williams-Gray, Caroline H., Marinus, Johan, Scherzer, Clemens R.
Publicado no Lancet Neurol (2017)

Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases

Por Witoelar, Aree, Jansen, Iris E., Wang, Yunpeng, Desikan, Rahul S., Gibbs, J. Raphael, Blauwendraat, Cornelis, Thompson, Wesley K., Hernandez, Dena G., Djurovic, Srdjan, Schork, Andrew J., Bettella, Francesco, Ellinghaus, David, Franke, Andre, Lie, Benedicte A., McEvoy, Linda K., Karlsen, Tom H., Lesage, Suzanne, Morris, Huw R., Brice, Alexis, Wood, Nicholas W., Heutink, Peter, Hardy, John, Singleton, Andrew B., Dale, Anders M., Gasser, Thomas, Andreassen, Ole A., Sharma, Manu
Publicado no JAMA Neurol (2017)

NeuroX, a Fast and Efficient Genotyping Platform for Investigation of Neurodegenerative Diseases

Por Nalls, Mike A., Bras, Jose, Hernandez, Dena G., Keller, Margaux F., Majounie, Elisa, Renton, Alan E., Saad, Mohamad, Jansen, Iris, Guerreiro, Rita, Lubbe, Steven, Plagnol, Vincent, Gibbs, J. Raphael, Schulte, Claudia, Pankratz, Nathan, Sutherland, Margaret, Bertram, Lars, Lill, Christina, DeStefano, Anita L., Faroud, Tatiana, Eriksson, Nicholas, Tung, Joyce Y., Connor, Edsall, Nichols, Noah, Brooks, Janet, Arepalli, Sampath, Pliner, Hannah, Letson, Chris, Heutink, Peter, Martinez, Maria, Gasser, Thomas, Traynor, Bryan J., Wood, Nick, Hardy, John, Singleton, Andrew B.
Publicado no Neurobiol Aging (2014)

Discovery and functional prioritization of Parkinson’s disease candidate genes from large-scale whole exome sequencing

Por Jansen, Iris E., Ye, Hui, Heetveld, Sasja, Lechler, Marie C., Michels, Helen, Seinstra, Renée I., Lubbe, Steven J., Drouet, Valérie, Lesage, Suzanne, Majounie, Elisa, Gibbs, J. Raphael, Nalls, Mike A., Ryten, Mina, Botia, Juan A., Vandrovcova, Jana, Simon-Sanchez, Javier, Castillo-Lizardo, Melissa, Rizzu, Patrizia, Blauwendraat, Cornelis, Chouhan, Amit K., Li, Yarong, Yogi, Puja, Amin, Najaf, van Duijn, Cornelia M., Morris, Huw R., Brice, Alexis, Singleton, Andrew B., David, Della C., Nollen, Ellen A., Jain, Shushant, Shulman, Joshua M., Heutink, Peter
Publicado no Genome Biol (2017)

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

Por Renton, Alan E., Majounie, Elisa, Waite, Adrian, Simón-Sánchez, Javier, Rollinson, Sara, Gibbs, J. Raphael, Schymick, Jennifer C., Laaksovirta, Hannu, van Swieten, John C., Myllykangas, Liisa, Kalimo, Hannu, Paetau, Anders, Abramzon, Yevgeniya, Remes, Anne M., Kaganovich, Alice, Scholz, Sonja W., Duckworth, Jamie, Ding, Jinhui, Harmer, Daniel W., Hernandez, Dena G., Johnson, Janel O., Mok, Kin, Ryten, Mina, Trabzuni, Danyah, Guerreiro, Rita J., Orrell, Richard W., Neal, James, Murray, Alex, Pearson, Justin, Jansen, Iris E., Sondervan, David, Seelaar, Harro, Blake, Derek, Young, Kate, Halliwell, Nicola, Callister, Janis, Toulson, Greg, Richardson, Anna, Gerhard, Alex, Snowden, Julie, Mann, David, Neary, David, Nalls, Michael A., Peuralinna, Terhi, Jansson, Lilja, Isoviita, Veli-Matti, Kaivorinne, Anna-Lotta, Hölttä-Vuori, Maarit, Ikonen, Elina, Sulkava, Raimo, Benatar, Michael, Wuu, Joanne, Chiò, Adriano, Restagno, Gabriella, Borghero, Giuseppe, Sabatelli, Mario, Heckerman, David, Rogaeva, Ekaterina, Zinman, Lorne, Rothstein, Jeffrey, Sendtner, Michael, Drepper, Carsten, Eichler, Evan E., Alkan, Can, Abdullaev, Zied, Pack, Svetlana D., Dutra, Amalia, Pak, Evgenia, Hardy, John, Singleton, Andrew, Williams, Nigel M., Heutink, Peter, Pickering-Brown, Stuart, Morris, Huw R., Tienari, Pentti J., Traynor, Bryan J.
Publicado em 2011

Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's

Por Liu, Ganqiang, Boot, Brendon, Locascio, Joseph J., Jansen, Iris E., Winder‐Rhodes, Sophie, Eberly, Shirley, Elbaz, Alexis, Brice, Alexis, Ravina, Bernard, van Hilten, Jacobus J., Cormier‐Dequaire, Florence, Corvol, Jean‐Christophe, Barker, Roger A., Heutink, Peter, Marinus, Johan, Williams‐Gray, Caroline H., Scherzer, Clemens R., Scherzer, C., Hyman, B.T., Ivinson, A.J., Trisini‐Lipsanopoulos, A., Franco, D., Burke, K., Sudarsky, L.R., Hayes, M.T., Umeh, C.C., Growdon, J.H., Schwarzschild, M.A., Hung, A.Y., Flaherty, A.W., Wills, A.‐M., Mejia, N.I., Gomperts, S.N., Khurana, V., Selkoe, D.J., Yi, T., Page, K., Liao, Z., Barker, R., Foltynie, T., Williams‐Gray, C.H., Mason, S., Winder‐Rhodes, S., Barker, R., Williams‐Gray, C.H., Breen, D., Cummins, G., Evans, J., Winder‐Rhodes, S., Corvol, J.‐C., Brice, A., Elbaz, A., Mallet, A., Vidailhet, M., Bonnet, A.‐M., Bonnet, C., Grabli, D., Hartmann, A., Klebe, S., Lacomblez, L., Mangone, G., Bourdain, F., Brandel, J.‐P., Derkinderen, P., Durif, F., Mesnage, V., Pico, F., Rascol, O., Forlani, S., Lesage, S., Tahiri, K., van Hilten, J.J., Marinus, J., Liao, Z., Page, K., Franco, D., Duong, K., Yi, T., Trisini‐Lipsanopoulos, A., Dong, X., Sudarsky, L.R., Hutten, S.J., Amr, S.S., Shoulson, I., Tanner, C.M., Lang, A.E., Nalls, M.A.
Publicado no Ann Neurol (2016)