Stratification and prediction of drug synergy based on target functional similarity

著者: Yang, Mi, Jaaks, Patricia, Dry, Jonathan, Garnett, Mathew, Menden, Michael P., Saez-Rodriguez, Julio
出版年 NPJ Syst Biol Appl (2020)

The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion

著者: Jaaks, Patricia, D’Alessandro, Valentina, Grob, Nicole, Büel, Sina, Hajdin, Katarina, Schäfer, Beat W., Bernasconi, Michele
出版年 PLoS One (2016)

Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

著者: Eduati, Federica, Jaaks, Patricia, Wappler, Jessica, Cramer, Thorsten, Merten, Christoph A, Garnett, Mathew J, Saez‐Rodriguez, Julio
出版年 Mol Syst Biol (2020)

Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

著者: Eduati, Federica, Jaaks, Patricia, Wappler, Jessica, Cramer, Thorsten, Merten, Christoph A, Garnett, Mathew J, Saez‐Rodriguez, Julio
出版年 Mol Syst Biol (2020)

The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells

著者: Jaaks, Patricia, Meier, Gianmarco, Alijaj, Nagjie, Brack, Eva, Bode, Peter, Koscielniak, Ewa, Wachtel, Marco, Schäfer, Beat W., Bernasconi, Michele
出版年 Oncotarget (2016)

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth

著者: Gierisch, Maria E., Pedot, Gloria, Walser, Franziska, Lopez-Garcia, Laura A., Jaaks, Patricia, Niggli, Felix K., Schäfer, Beat W.
出版年 Sci Rep (2019)

Transcription factor activities enhance markers of drug sensitivity in cancer

著者: Garcia-Alonso, Luz, Iorio, Francesco, Matchan, Angela, Fonseca, Nuno, Jaaks, Patricia, Peat, Gareth, Pignatelli, Miguel, Falcone, Fiammetta, Benes, Cyril H., Dunham, Ian, Bignell, Graham, McDade, Simon S., Garnett, Mathew J., Saez-Rodriguez, Julio
出版年 Cancer Res (2018)

Integrated cross-study datasets of genetic dependencies in cancer

著者: Pacini, Clare, Dempster, Joshua M., Boyle, Isabella, Gonçalves, Emanuel, Najgebauer, Hanna, Karakoc, Emre, van der Meer, Dieudonne, Barthorpe, Andrew, Lightfoot, Howard, Jaaks, Patricia, McFarland, James M., Garnett, Mathew J., Tsherniak, Aviad, Iorio, Francesco
出版年 Nat Commun (2021)

SLFN11 informs on standard of care and novel treatments in a wide range of cancer models

著者: Winkler, Claudia, Armenia, Joshua, Jones, Gemma N., Tobalina, Luis, Sale, Matthew J., Petreus, Tudor, Baird, Tarrion, Serra, Violeta, Wang, Anderson T., Lau, Alan, Garnett, Mathew J., Jaaks, Patricia, Coker, Elizabeth A., Pierce, Andrew J., O’Connor, Mark J., Leo, Elisabetta
出版年 Br J Cancer (2020)

Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens

著者: Gonçalves, Emanuel, Segura‐Cabrera, Aldo, Pacini, Clare, Picco, Gabriele, Behan, Fiona M, Jaaks, Patricia, Coker, Elizabeth A, van der Meer, Donny, Barthorpe, Andrew, Lightfoot, Howard, Mironenko, Tatiana, Beck, Alexandra, Richardson, Laura, Yang, Wanjuan, Lleshi, Ermira, Hall, James, Tolley, Charlotte, Hall, Caitlin, Mali, Iman, Thomas, Frances, Morris, James, Leach, Andrew R, Lynch, James T, Sidders, Ben, Crafter, Claire, Iorio, Francesco, Fawell, Stephen, Garnett, Mathew J
出版年 Mol Syst Biol (2020)