Targeting energy metabolism in cancer stem cells - progress and challenges in leukemia and solid tumors

by Jones, Courtney L., Inguva, Anagha, Jordan, Craig T.
Published in Cell Stem Cell (2021)

KRAS insertion mutations are oncogenic and exhibit distinct functional properties

by White, Yasmine, Bagchi, Aditi, Van Ziffle, Jessica, Inguva, Anagha, Bollag, Gideon, Zhang, Chao, Carias, Heidi, Dickens, David, Loh, Mignon, Shannon, Kevin, Firestone, Ari J.
Published in Nat Commun (2016)

Genetic disruption of N-Ras(G12D) palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice

by Zambetti, Noemi A., Firestone, Ari J., Remsberg, Jarrett R., Huang, Benjamin J., Wong, Jasmine C., Long, Amanda M., Predovic, Marina, Suciu, Radu M., Inguva, Anagha, Kogan, Scott C., Haigis, Kevin M., Cravatt, Benjamin F., Shannon, Kevin
Published in Blood (2020)

The hepatic microenvironment uniquely protects leukemia cells through induction of growth and survival pathways mediated by LIPG

by Ye, Haobin, Minhajuddin, Mohammad, Krug, Anna, Pei, Shanshan, Chou, Chih-Hsing, Culp-Hill, Rachel, Ponder, Jessica, De Bloois, Erik, Schniedewind, Björn, Amaya, Maria L., Inguva, Anagha, Stevens, Brett M., Pollyea, Daniel A., Christians, Uwe, Grimes, H. Leighton, D’Alessandro, Angelo, Jordan, Craig T.
Published in Cancer Discov (2020)

AMPK/FIS1-mediated mitophagy is required for self-renewal of human AML stem cells

by Pei, Shanshan, Minhajuddin, Mohammad, Adane, Biniam, Khan, Nabilah, Stevens, Brett M., Mack, Stephen C., Lai, Sisi, Rich, Jeremy N., Inguva, Anagha, Shannon, Kevin M., Kim, Hyunmin, Tan, Aik-Choon, Myers, Jason R., Ashton, John M., Neff, Tobias, Pollyea, Daniel A., Smith, Clayton A., Jordan, Craig T.
Published in Cell Stem Cell (2018)

Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells

by Jones, Courtney L., Stevens, Brett M., Pollyea, Daniel A., Culp-Hill, Rachel, Reisz, Julie A., Nemkov, Travis, Gehrke, Sarah, Gamboni, Fabia, Krug, Anna, Winters, Amanda, Pei, Shanshan, Gustafson, Annika, Ye, Haobin, Inguva, Anagha, Amaya, Maria, Minhajuddin, Mohammad, Abbott, Diana, Becker, Michael W., DeGregori, James, Smith, Clayton, D'Alessandro, Angelo, Jordan, Craig T.
Published in Cell Stem Cell (2020)

Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Acute Myeloid Leukemia Patients

by Pei, Shanshan, Pollyea, Daniel A., Gustafson, Annika, Stevens, Brett M., Minhajuddin, Mohammad, Fu, Rui, Riemondy, Kent A., Gillen, Austin E., Sheridan, Ryan M., Kim, Jihye, Costello, James C., Amaya, Maria L., Inguva, Anagha, Winters, Amanda, Ye, Haobin, Krug, Anna, Jones, Courtney L., Adane, Biniam, Khan, Nabilah, Ponder, Jessica, Schowinsky, Jeffrey, Abbott, Diana, Hammes, Andrew, Myers, Jason R., Ashton, John M., Nemkov, Travis, D’Alessandro, Angelo, Gutman, Jonathan A., Ramsey, Haley E., Savona, Michael R., Smith, Clayton A., Jordan, Craig T.
Published in Cancer Discov (2020)