Targeting energy metabolism in cancer stem cells - progress and challenges in leukemia and solid tumors

per Jones, Courtney L., Inguva, Anagha, Jordan, Craig T.
Publicat a Cell Stem Cell (2021)

KRAS insertion mutations are oncogenic and exhibit distinct functional properties

per White, Yasmine, Bagchi, Aditi, Van Ziffle, Jessica, Inguva, Anagha, Bollag, Gideon, Zhang, Chao, Carias, Heidi, Dickens, David, Loh, Mignon, Shannon, Kevin, Firestone, Ari J.
Publicat a Nat Commun (2016)

Genetic disruption of N-Ras(G12D) palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice

per Zambetti, Noemi A., Firestone, Ari J., Remsberg, Jarrett R., Huang, Benjamin J., Wong, Jasmine C., Long, Amanda M., Predovic, Marina, Suciu, Radu M., Inguva, Anagha, Kogan, Scott C., Haigis, Kevin M., Cravatt, Benjamin F., Shannon, Kevin
Publicat a Blood (2020)

The hepatic microenvironment uniquely protects leukemia cells through induction of growth and survival pathways mediated by LIPG

per Ye, Haobin, Minhajuddin, Mohammad, Krug, Anna, Pei, Shanshan, Chou, Chih-Hsing, Culp-Hill, Rachel, Ponder, Jessica, De Bloois, Erik, Schniedewind, Björn, Amaya, Maria L., Inguva, Anagha, Stevens, Brett M., Pollyea, Daniel A., Christians, Uwe, Grimes, H. Leighton, D’Alessandro, Angelo, Jordan, Craig T.
Publicat a Cancer Discov (2020)

AMPK/FIS1-mediated mitophagy is required for self-renewal of human AML stem cells

per Pei, Shanshan, Minhajuddin, Mohammad, Adane, Biniam, Khan, Nabilah, Stevens, Brett M., Mack, Stephen C., Lai, Sisi, Rich, Jeremy N., Inguva, Anagha, Shannon, Kevin M., Kim, Hyunmin, Tan, Aik-Choon, Myers, Jason R., Ashton, John M., Neff, Tobias, Pollyea, Daniel A., Smith, Clayton A., Jordan, Craig T.
Publicat a Cell Stem Cell (2018)

Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells

per Jones, Courtney L., Stevens, Brett M., Pollyea, Daniel A., Culp-Hill, Rachel, Reisz, Julie A., Nemkov, Travis, Gehrke, Sarah, Gamboni, Fabia, Krug, Anna, Winters, Amanda, Pei, Shanshan, Gustafson, Annika, Ye, Haobin, Inguva, Anagha, Amaya, Maria, Minhajuddin, Mohammad, Abbott, Diana, Becker, Michael W., DeGregori, James, Smith, Clayton, D'Alessandro, Angelo, Jordan, Craig T.
Publicat a Cell Stem Cell (2020)

Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Acute Myeloid Leukemia Patients

per Pei, Shanshan, Pollyea, Daniel A., Gustafson, Annika, Stevens, Brett M., Minhajuddin, Mohammad, Fu, Rui, Riemondy, Kent A., Gillen, Austin E., Sheridan, Ryan M., Kim, Jihye, Costello, James C., Amaya, Maria L., Inguva, Anagha, Winters, Amanda, Ye, Haobin, Krug, Anna, Jones, Courtney L., Adane, Biniam, Khan, Nabilah, Ponder, Jessica, Schowinsky, Jeffrey, Abbott, Diana, Hammes, Andrew, Myers, Jason R., Ashton, John M., Nemkov, Travis, D’Alessandro, Angelo, Gutman, Jonathan A., Ramsey, Haley E., Savona, Michael R., Smith, Clayton A., Jordan, Craig T.
Publicat a Cancer Discov (2020)