Chemically modified peptides and proteins - critical considerations for oral delivery

Autor Buckley, Stephen T., Hubálek, František, Rahbek, Ulrik Lytt
Vydáno v Tissue Barriers (2016)

Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures

Autor Binda, Claudia, Li, Min, Hubálek, Frantisek, Restelli, Nadia, Edmondson, Dale E., Mattevi, Andrea
Vydáno 2003

Investigation of the Physico-Chemical Properties that Enable Co-Formulation of Basal Insulin Degludec with Fast-Acting Insulin Aspart

Autor Havelund, Svend, Ribel, Ulla, Hubálek, František, Hoeg-Jensen, Thomas, Wahlund, Per-Olof, Jonassen, Ib
Vydáno v Pharm Res (2015)

Binding of Rasagiline-related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis

Autor Binda, Claudia, Hubálek, Frantisek, Li, Min, Herzig, Yaacov, Sterling, Jeffrey, Edmondson, Dale E., Mattevi, Andrea
Vydáno 2005

WD40 Repeat Proteins Striatin and S/G(2) Nuclear Autoantigen Are Members of a Novel Family of Calmodulin-binding Proteins That Associate with Protein Phosphatase 2A

Autor Moreno, Carlos S., Park, Susan, Nelson, Kasey, Ashby, Danita, Hubalek, Frantisek, Lane, William S., Pallas, David C.
Vydáno 2000

cAMP-Dependent Protein Kinase Inhibits mGluR2 Coupling to G-Proteins by Direct Receptor Phosphorylation

Autor Schaffhauser, Hervé, Cai, Zhaohui, Hubalek, Frantisek, Macek, Thomas A., Pohl, Jan, Murphy, Thomas J., Conn, P. Jeffrey
Vydáno v J Neurosci (2000)

Additional disulfide bonds in insulin: Prediction, recombinant expression, receptor binding affinity, and stability

Autor Vinther, Tine N, Pettersson, Ingrid, Huus, Kasper, Schlein, Morten, Steensgaard, Dorte B, Sørensen, Anders, Jensen, Knud J, Kjeldsen, Thomas, Hubalek, František
Vydáno v Protein Sci (2015)

Novel Covalently Linked Insulin Dimer Engineered to Investigate the Function of Insulin Dimerization

Autor Vinther, Tine N., Norrman, Mathias, Strauss, Holger M., Huus, Kasper, Schlein, Morten, Pedersen, Thomas Å., Kjeldsen, Thomas, Jensen, Knud J., Hubálek, František
Vydáno 2012

Dually Reactive Long Recombinant Linkers for Bioconjugations as an Alternative to PEG

Autor Kjeldsen, Thomas, Hogendorf, Wouter F. J., Tornøe, Christian W., Anderson, Jonathan, Hubalek, Frantisek, Stidsen, Carsten E., Sorensen, Jan L., Hoeg-Jensen, Thomas
Vydáno v ACS Omega (2020)

Cyclic AMP-dependent protein kinase phosphorylates group III metabotropic glutamate receptors and inhibits their function as presynaptic receptors

Autor Cai, Zhaohui, Saugstad, Julie A., Sorensen, Scott D., Ciombor, Kelly J., Zhang, Congxiao, Schaffhauser, Hervé, Hubalek, Frantisek, Pohl, Jan, Duvoisin, Robert M., Conn, P. Jeffrey
Vydáno 2001

Insulin analog with additional disulfide bond has increased stability and preserved activity

Autor Vinther, Tine N, Norrman, Mathias, Ribel, Ulla, Huus, Kasper, Schlein, Morten, Steensgaard, Dorte B, Pedersen, Thomas Å, Pettersson, Ingrid, Ludvigsen, Svend, Kjeldsen, Thomas, Jensen, Knud J, Hubálek, František
Vydáno 2013

An ingestible self-orienting system for oral delivery of macromolecules

Autor Abramson, Alex, Caffarel-Salvador, Ester, Khang, Minsoo, Dellal, David, Silverstein, David, Gao, Yuan, Frederiksen, Morten Revsgaard, Vegge, Andreas, Hubálek, Frantisek, Water, Jorrit J., Friderichsen, Anders V., Fels, Johannes, Kirk, Rikke Kaae, Cleveland, Cody, Collins, Joy, Tamang, Siddartha, Hayward, Alison, Landh, Tomas, Buckley, Stephen T., Roxhed, Niclas, Rahbek, Ulrik, Langer, Robert, Traverso, Giovanni
Vydáno v Science (2019)

Molecular engineering of safe and efficacious oral basal insulin

Autor Hubálek, Frantisek, Refsgaard, Hanne H. F., Gram-Nielsen, Sanne, Madsen, Peter, Nishimura, Erica, Münzel, Martin, Brand, Christian Lehn, Stidsen, Carsten Enggaard, Claussen, Christian Hove, Wulff, Erik Max, Pridal, Lone, Ribel, Ulla, Kildegaard, Jonas, Porsgaard, Trine, Johansson, Eva, Steensgaard, Dorte Bjerre, Hovgaard, Lars, Glendorf, Tine, Hansen, Bo Falck, Jensen, Maja Kirkegaard, Nielsen, Peter Kresten, Ludvigsen, Svend, Rugh, Susanne, Garibay, Patrick W., Moore, Mary Courtney, Cherrington, Alan D., Kjeldsen, Thomas
Vydáno v Nat Commun (2020)

Author Correction: Molecular engineering of safe and efficacious oral basal insulin

Autor Hubálek, Frantisek, Refsgaard, Hanne H. F., Gram-Nielsen, Sanne, Madsen, Peter, Nishimura, Erica, Münzel, Martin, Brand, Christian Lehn, Stidsen, Carsten Enggaard, Claussen, Christian Hove, Wulff, Erik Max, Pridal, Lone, Ribel, Ulla, Kildegaard, Jonas, Porsgaard, Trine, Johansson, Eva, Steensgaard, Dorte Bjerre, Hovgaard, Lars, Glendorf, Tine, Hansen, Bo Falck, Jensen, Maja Kirkegaard, Nielsen, Peter Kresten, Ludvigsen, Svend, Rugh, Susanne, Garibay, Patrick W., Moore, Mary Courtney, Cherrington, Alan D., Kjeldsen, Thomas
Vydáno v Nat Commun (2020)