Novel Covalently Linked Insulin Dimer Engineered to Investigate the Function of Insulin Dimerization

An ingenious system evolved to facilitate insulin binding to the insulin receptor as a monomer and at the same time ensure sufficient stability of insulin during storage. Insulin dimer is the cornerstone of this system. Insulin dimer is relatively weak, which ensures dissociation into monomers in th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vinther, Tine N., Norrman, Mathias, Strauss, Holger M., Huus, Kasper, Schlein, Morten, Pedersen, Thomas Å., Kjeldsen, Thomas, Jensen, Knud J., Hubálek, František
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281904/
https://ncbi.nlm.nih.gov/pubmed/22363506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030882
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