WJ9708012 exerts anticancer activity through PKC-α related crosstalk of mitochondrial and endoplasmic reticulum stresses in human hormone-refractory prostate cancer cells

Por Kuo, Ting-chun, Huang, Wei-jan, Guh, Jih-hwa
Publicado em 2011

Acacetin Inhibits Glutamate Release and Prevents Kainic Acid-Induced Neurotoxicity in Rats

Por Lin, Tzu-Yu, Huang, Wei-Jan, Wu, Chia-Chan, Lu, Cheng-Wei, Wang, Su-Jane
Publicado em 2014

Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative

Por Chen, Liang-Chieh, Hsu, Kai-Cheng, Chiou, Lih-Chu, Tseng, Hui-Ju, Huang, Wei-Jan
Publicado no Molecules (2017)

Chemical Constituents Analysis and Antidiabetic Activity Validation of Four Fern Species from Taiwan

Por Chen, Chen-Yu, Chiu, Fu-Yu, Lin, Yenshou, Huang, Wei-Jan, Hsieh, Po-Shiuan, Hsu, Feng-Lin
Publicado no Int J Mol Sci (2015)

WMJ–S–001, a novel aliphatic hydroxamate derivative, exhibits anti-inflammatory properties via MKP-1 in LPS-stimulated RAW264.7 macrophages

Por Chen, Wei-Chuan, Yen, Chia-Sheng, Huang, Wei-Jan, Hsu, Ya-Fen, Ou, George, Hsu, Ming-Jen
Publicado no Br J Pharmacol (2015)

The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death

Por Huang, Yu-Han, Huang, Shiu-Wen, Hsu, Ya-Fen, Ou, George, Huang, Wei-Jan, Hsu, Ming-Jen
Publicado no Sci Rep (2015)

The Novel HDAC8 Inhibitor WK2-16 Attenuates Lipopolysaccharide-Activated Matrix Metalloproteinase-9 Expression in Human Monocytic Cells and Improves Hypercytokinemia In Vivo

Por Jan, Jing-Shiun, Chou, Yung-Chen, Cheng, Yu-Wen, Chen, Chih-Kuang, Huang, Wei-Jan, Hsiao, George
Publicado no Int J Mol Sci (2017)

Low-Luminance Blue Light-Enhanced Phototoxicity in A2E-Laden RPE Cell Cultures and Rats

Por Lin, Cheng-Hui, Wu, Man-Ru, Huang, Wei-Jan, Chow, Diana Shu-Lian, Hsiao, George, Cheng, Yu-Wen
Publicado no Int J Mol Sci (2019)

Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells i...

Por Chiu, Hui-Wen, Yeh, Ya-Ling, Wang, Yi-Ching, Huang, Wei-Jan, Ho, Sheng-Yow, Lin, Pinpin, Wang, Ying-Jan
Publicado no Mol Cancer (2016)

WMJ‐8‐B, a novel hydroxamate derivative, induces MDA‐MB‐231 breast cancer cell death via the SHP‐1‐STAT3‐survivin cascade

Por Chuang, Yu‐Fan, Huang, Shiu‐Wen, Hsu, Ya‐Fen, Yu, Meng‐Chieh, Ou, George, Huang, Wei‐Jan, Hsu, Ming‐Jen
Publicado no Br J Pharmacol (2017)

HDAC8 Inhibitor WK2-16 Therapeutically Targets Lipopolysaccharide-Induced Mouse Model of Neuroinflammation and Microglial Activation

Por Lin, Fan-Li, Yen, Jing-Lun, Kuo, Yu-Cheng, Kang, Jaw-Jou, Cheng, Yu-Wen, Huang, Wei-Jan, Hsiao, George
Publicado no Int J Mol Sci (2019)

Evaluation of the Antihyperuricemic Activity of Phytochemicals from Davallia formosana by Enzyme Assay and Hyperuricemic Mice Model

Por Chen, Chen-Yu, Huang, Chi-Chang, Tsai, Keng-Chang, Huang, Wei-Jan, Huang, Wen-Ching, Hsu, Yu-Chen, Hsu, Feng-Lin
Publicado em 2014

N-Hydroxycinnamide Derivatives of Osthole Ameliorate Hyperglycemia through Activation of AMPK and p38 MAPK

Por Lee, Wei-Hwa, Wu, Hsueh-Hsia, Huang, Wei-Jan, Li, Yi-Ning, Lin, Ren-Jye, Lin, Shyr-Yi, Liang, Yu-Chih
Publicado no Molecules (2015)

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1

Por Chang, Yi-Fang, Hsu, Ya-Fen, Chiu, Pei-Ting, Huang, Wei-Jan, Huang, Shiu-Wen, Ou, George, Sheu, Joen-Rong, Hsu, Ming-Jen
Publicado no Oncotarget (2014)

Evaluation of Antioxidant and Free Radical Scavenging Capacities of Polyphenolics from Pods of Caesalpinia pulcherrima

Por Hsu, Feng-Lin, Huang, Wei-Jan, Wu, Tzu-Hua, Lee, Mei-Hsien, Chen, Lih-Chi, Lu, Hsiao-Jen, Hou, Wen-Chi, Lin, Mei-Hsiang
Publicado em 2012

Clerodendrum inerme Leaf Extract Alleviates Animal Behaviors, Hyperlocomotion, and Prepulse Inhibition Disruptions, Mimicking Tourette Syndrome and Schizophrenia

Por Chen, Hon-Lie, Lee, Hsin-Jung, Huang, Wei-Jan, Chou, Jui-Feng, Fan, Pi-Chuan, Du, Jung-Chieh, Ku, Yuan-Ling, Chiou, Lih-Chu
Publicado em 2012

A Taiwanese Propolis Derivative Induces Apoptosis through Inducing Endoplasmic Reticular Stress and Activating Transcription Factor-3 in Human Hepatoma Cells

Por Suk, Fat-Moon, Lien, Gi-Shih, Huang, Wei-Jan, Chen, Chia-Nan, Lu, Shao-Yu, Yang, Ying-Chen, Yan, Ming-De, Liang, Yu-Chih
Publicado em 2013

Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach

Por Hsu, Kai-Cheng, Liu, Chang-Yi, Lin, Tony Eight, Hsieh, Jui-Hua, Sung, Tzu-Ying, Tseng, Hui-Ju, Yang, Jinn-Moon, Huang, Wei-Jan
Publicado no Sci Rep (2017)

Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Enhances Radiosensitivity and Suppresses Lung Metastasis in Breast Cancer In Vitro and In Vivo

Por Chiu, Hui-Wen, Yeh, Ya-Ling, Wang, Yi-Ching, Huang, Wei-Jan, Chen, Yi-An, Chiou, Yi-Shiou, Ho, Sheng-Yow, Lin, Pinpin, Wang, Ying-Jan
Publicado em 2013

A Novel Hydroxamate-Based Compound WMJ-J-09 Causes Head and Neck Squamous Cell Carcinoma Cell Death via LKB1-AMPK-p38MAPK-p63-Survivin Cascade

Por Yen, Chia-Sheng, Choy, Cheuk-Sing, Huang, Wei-Jan, Huang, Shiu-Wen, Lai, Pin-Ye, Yu, Meng-Chieh, Shiue, Ching, Hsu, Ya-Fen, Hsu, Ming-Jen
Publicado no Front Pharmacol (2018)