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Low-Luminance Blue Light-Enhanced Phototoxicity in A2E-Laden RPE Cell Cultures and Rats

N-retinylidene-N-retinylethanolamine (A2E) and other bisretinoids are components of lipofuscin and accumulate in retinal pigment epithelial (RPE) cells—these adducts are recognized in the pathogenesis of retinal degeneration. Further, blue light-emitting diode (LED) light (BLL)-induced retinal toxic...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lin, Cheng-Hui, Wu, Man-Ru, Huang, Wei-Jan, Chow, Diana Shu-Lian, Hsiao, George, Cheng, Yu-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6480556/
https://ncbi.nlm.nih.gov/pubmed/30979028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20071799
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