Loss of Notch1 activity inhibits prostate cancer growth and metastasis and sensitizes prostate cancer cells to anti-androgen therapies

по Rice, Meghan A., Hsu, En-Chi, Aslan, Merve, Ghoochani, Ali, Su, Austin, Stoyanova, Tanya
Опубликовано в: Mol Cancer Ther (2019)

Identification and Characterization of a Novel Integrin-Linked Kinase Inhibitor

по Lee, Su-Lin, Hsu, En-Chi, Chou, Chih-Chien, Chuang, Hsiao-Ching, Bai, Li-Yuan, Kulp, Samuel K., Chen, Ching-Shih
Опубликовано 2011

Ferroptosis inducers are a novel therapeutic approach for advanced prostate cancer

по Ghoochani, Ali, Hsu, En-Chi, Aslan, Merve, Rice, Meghan A., Nguyen, Holly M., Brooks, James D., Corey, Eva, Paulmurugan, Ramasamy, Stoyanova, Tanya
Опубликовано в: Cancer Res (2021)

Targeting Energy Metabolic and Oncogenic Signaling Pathways in Triple-negative Breast Cancer by a Novel Adenosine Monophosphate-activated Protein Kinase (AMPK) Activator

по Lee, Kuen-Haur, Hsu, En-Chi, Guh, Jih-Hwa, Yang, Hsiao-Ching, Wang, Dasheng, Kulp, Samuel K., Shapiro, Charles L., Chen, Ching-Shih
Опубликовано 2011

Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines

по Lee, Su-Lin, Chou, Chih-Chien, Chuang, Hsiao-Ching, Hsu, En-Chi, Chiu, Po-Chen, Kulp, Samuel K., Byrd, John C., Chen, Ching-Shih
Опубликовано 2013

Plectin is a Regulator of Prostate Cancer Growth and Metastasis

по Buckup, Mark, Rice, Meghan A., Hsu, En-Chi, Garcia-Marques, Fernando, Liu, Shiqin, Aslan, Merve, Bermudez, Abel, Huang, Jiaoti, Pitteri, Sharon J., Stoyanova, Tanya
Опубликовано в: Oncogene (2020)

Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6–Abundant Breast Cancer Cells by Regulating γ-Secretase–Mediated Notch1 Activation in Caveolae()()

по Hsu, En-Chi, Kulp, Samuel K., Huang, Han-Li, Tu, Huang-Ju, Salunke, Santosh B., Sullivan, Nicholas J., Sun, Duxin, Wicha, Max S., Shapiro, Charles L., Chen, Ching-Shih
Опубликовано в: Neoplasia (2015)

MCM2-7 complex is a novel druggable target for neuroendocrine prostate cancer

по Hsu, En-Chi, Shen, Michelle, Aslan, Merve, Liu, Shiqin, Kumar, Manoj, Garcia-Marques, Fernando, Nguyen, Holly M., Nolley, Rosalie, Pitteri, Sharon J., Corey, Eva, Brooks, James D., Stoyanova, Tanya
Опубликовано в: Sci Rep (2021)

Discovery of CASP8 as a potential biomarker for high-risk prostate cancer through a high-multiplex immunoassay

по Liu, Shiqin, Garcia-Marques, Fernando, Zhang, Chiyuan Amy, Lee, Jordan John, Nolley, Rosalie, Shen, Michelle, Hsu, En-Chi, Aslan, Merve, Koul, Kashyap, Pitteri, Sharon J., Brooks, James D., Stoyanova, Tanya
Опубликовано в: Sci Rep (2021)

PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression

по Lang, Yaw-Dong, Chen, Hsin-Yi, Ho, Chun-Ming, Shih, Jou-Ho, Hsu, En-Chi, Shen, Roger, Lee, Yu-Ching, Chen, Jyun-Wei, Wu, Cheng-Yen, Yeh, Hsi-Wen, Chen, Ruey-Hwa, Jou, Yuh-Shan
Опубликовано в: Nat Commun (2019)

Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability

по Chao, Min-Wu, Chu, Po-Chen, Chuang, Hsiao-Ching, Shen, Fang-Hsiu, Chou, Chih-Chien, Hsu, En-Chi, Himmel, Lauren E., Huang, Han-Li, Tu, Huang-Ju, Kulp, Samuel K., Teng, Che-Ming, Chen, Ching-Shih
Опубликовано в: Oncotarget (2015)

Retraction: Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability

по Chao, Min-Wu, Chu, Po-Chen, Chuang, Hsiao-Ching, Shen, Fang-Hsiu, Chou, Chih-Chien, Hsu, En-Chi, Himmel, Lauren E., Huang, Han-Li, Tu, Huang-Ju, Kulp, Samuel K., Teng, Che-Ming, Chen, Ching-Shih
Опубликовано в: Oncotarget (2020)

Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer

по Liu, Shiqin, Shen, Michelle, Hsu, En-Chi, Zhang, Chiyuan Amy, Garcia-Marques, Fernando, Nolley, Rosalie, Koul, Kashyap, Rice, Meghan A., Aslan, Merve, Pitteri, Sharon J., Massie, Charlie, George, Anne, Brooks, James D., Gnanapragasam, Vincent J., Stoyanova, Tanya
Опубликовано в: Br J Cancer (2020)

Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia

по Tseng, Yu-Chou, Kulp, Samuel K., Lai, I-Lu, Hsu, En-Chi, He, Wei A., Frankhouser, David E., Yan, Pearlly S., Mo, Xiaokui, Bloomston, Mark, Lesinski, Gregory B., Marcucci, Guido, Guttridge, Denis C., Bekaii-Saab, Tanios, Chen, Ching-Shih
Опубликовано в: J Natl Cancer Inst (2015)

In vivo imaging of methionine aminopeptidase II for prostate cancer risk stratification

по Xie, Jinghang, Rice, Meghan A., Chen, Zixin, Cheng, Yunfeng, Hsu, En-Chi, Chen, Min, Song, Guosheng, Cui, Liyang, Zhou, Kaixiang, Castillo, Jessa B., Zhang, Chiyuan A., Shen, Bin, Chin, Frederick T., Kunder, Christian A., Brooks, James D., Stoyanova, Tanya, Rao, Jianghong
Опубликовано в: Cancer Res (2021)

Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer

по Hsu, En-Chi, Kulp, Samuel K., Huang, Han-Li, Tu, Huang-Ju, Chao, Min-Wu, Tseng, Yu-Chou, Yang, Ming-Chen, Salunke, Santosh B., Sullivan, Nicholas J., Chen, Wen-Chung, Zhang, Jianying, Teng, Che-Ming, Fu, Wen-Mei, Sun, Duxin, Wicha, Max S., Shapiro, Charles L., Chen, Ching-Shih
Опубликовано в: Carcinogenesis (2016)

The Exosome Total Isolation Chip

по Liu, Fei, Vermesh, Ophir, Mani, Vigneshwaran, Ge, Tianjia J., Madsen, Steven J., Sabour, Andrew, Hsu, En-Chi, Gowrishankar, Gayatri, Kanada, Masamitsu, Jokerst, Jesse V., Sierra, Raymond G., Chang, Edwin, Lau, Kenneth, Sridhar, Kaushik, Bermudez, Abel, Pitteri, Sharon J., Stoyanova, Tanya, Sinclair, Robert, Nair, Viswam S., Gambhir, Sanjiv S., Demirci, Utkan
Опубликовано в: ACS Nano (2017)

Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1

по Hsu, En-Chi, Rice, Meghan A., Bermudez, Abel, Marques, Fernando Jose Garcia, Aslan, Merve, Liu, Shiqin, Ghoochani, Ali, Zhang, Chiyuan Amy, Chen, Yun-Sheng, Zlitni, Aimen, Kumar, Sahil, Nolley, Rosalie, Habte, Frezghi, Shen, Michelle, Koul, Kashyap, Peehl, Donna M., Zoubeidi, Amina, Gambhir, Sanjiv S., Kunder, Christian A., Pitteri, Sharon J., Brooks, James D., Stoyanova, Tanya
Опубликовано в: Proc Natl Acad Sci U S A (2020)

Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer

по Stoyanova, Tanya, Riedinger, Mireille, Lin, Shu, Faltermeier, Claire M., Smith, Bryan A., Zhang, Kelvin X., Going, Catherine C., Goldstein, Andrew S., Lee, John K., Drake, Justin M., Rice, Meghan A., Hsu, En-Chi, Nowroozizadeh, Behdokht, Castor, Brandon, Orellana, Sandra Y., Blum, Steven M., Cheng, Donghui, Pienta, Kenneth J., Reiter, Robert E., Pitteri, Sharon J., Huang, Jiaoti, Witte, Owen N.
Опубликовано в: Proc Natl Acad Sci U S A (2016)