Loss of Notch1 activity inhibits prostate cancer growth and metastasis and sensitizes prostate cancer cells to anti-androgen therapies

le Rice, Meghan A., Hsu, En-Chi, Aslan, Merve, Ghoochani, Ali, Su, Austin, Stoyanova, Tanya
Foilsithe in Mol Cancer Ther (2019)

Identification and Characterization of a Novel Integrin-Linked Kinase Inhibitor

le Lee, Su-Lin, Hsu, En-Chi, Chou, Chih-Chien, Chuang, Hsiao-Ching, Bai, Li-Yuan, Kulp, Samuel K., Chen, Ching-Shih
Foilsithe 2011

Ferroptosis inducers are a novel therapeutic approach for advanced prostate cancer

le Ghoochani, Ali, Hsu, En-Chi, Aslan, Merve, Rice, Meghan A., Nguyen, Holly M., Brooks, James D., Corey, Eva, Paulmurugan, Ramasamy, Stoyanova, Tanya
Foilsithe in Cancer Res (2021)

Targeting Energy Metabolic and Oncogenic Signaling Pathways in Triple-negative Breast Cancer by a Novel Adenosine Monophosphate-activated Protein Kinase (AMPK) Activator

le Lee, Kuen-Haur, Hsu, En-Chi, Guh, Jih-Hwa, Yang, Hsiao-Ching, Wang, Dasheng, Kulp, Samuel K., Shapiro, Charles L., Chen, Ching-Shih
Foilsithe 2011

Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines

le Lee, Su-Lin, Chou, Chih-Chien, Chuang, Hsiao-Ching, Hsu, En-Chi, Chiu, Po-Chen, Kulp, Samuel K., Byrd, John C., Chen, Ching-Shih
Foilsithe 2013

Plectin is a Regulator of Prostate Cancer Growth and Metastasis

le Buckup, Mark, Rice, Meghan A., Hsu, En-Chi, Garcia-Marques, Fernando, Liu, Shiqin, Aslan, Merve, Bermudez, Abel, Huang, Jiaoti, Pitteri, Sharon J., Stoyanova, Tanya
Foilsithe in Oncogene (2020)

Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6–Abundant Breast Cancer Cells by Regulating γ-Secretase–Mediated Notch1 Activation in Caveolae()()

le Hsu, En-Chi, Kulp, Samuel K., Huang, Han-Li, Tu, Huang-Ju, Salunke, Santosh B., Sullivan, Nicholas J., Sun, Duxin, Wicha, Max S., Shapiro, Charles L., Chen, Ching-Shih
Foilsithe in Neoplasia (2015)

MCM2-7 complex is a novel druggable target for neuroendocrine prostate cancer

le Hsu, En-Chi, Shen, Michelle, Aslan, Merve, Liu, Shiqin, Kumar, Manoj, Garcia-Marques, Fernando, Nguyen, Holly M., Nolley, Rosalie, Pitteri, Sharon J., Corey, Eva, Brooks, James D., Stoyanova, Tanya
Foilsithe in Sci Rep (2021)

Discovery of CASP8 as a potential biomarker for high-risk prostate cancer through a high-multiplex immunoassay

le Liu, Shiqin, Garcia-Marques, Fernando, Zhang, Chiyuan Amy, Lee, Jordan John, Nolley, Rosalie, Shen, Michelle, Hsu, En-Chi, Aslan, Merve, Koul, Kashyap, Pitteri, Sharon J., Brooks, James D., Stoyanova, Tanya
Foilsithe in Sci Rep (2021)

PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression

le Lang, Yaw-Dong, Chen, Hsin-Yi, Ho, Chun-Ming, Shih, Jou-Ho, Hsu, En-Chi, Shen, Roger, Lee, Yu-Ching, Chen, Jyun-Wei, Wu, Cheng-Yen, Yeh, Hsi-Wen, Chen, Ruey-Hwa, Jou, Yuh-Shan
Foilsithe in Nat Commun (2019)

Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability

le Chao, Min-Wu, Chu, Po-Chen, Chuang, Hsiao-Ching, Shen, Fang-Hsiu, Chou, Chih-Chien, Hsu, En-Chi, Himmel, Lauren E., Huang, Han-Li, Tu, Huang-Ju, Kulp, Samuel K., Teng, Che-Ming, Chen, Ching-Shih
Foilsithe in Oncotarget (2015)

Retraction: Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability

le Chao, Min-Wu, Chu, Po-Chen, Chuang, Hsiao-Ching, Shen, Fang-Hsiu, Chou, Chih-Chien, Hsu, En-Chi, Himmel, Lauren E., Huang, Han-Li, Tu, Huang-Ju, Kulp, Samuel K., Teng, Che-Ming, Chen, Ching-Shih
Foilsithe in Oncotarget (2020)

Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer

le Liu, Shiqin, Shen, Michelle, Hsu, En-Chi, Zhang, Chiyuan Amy, Garcia-Marques, Fernando, Nolley, Rosalie, Koul, Kashyap, Rice, Meghan A., Aslan, Merve, Pitteri, Sharon J., Massie, Charlie, George, Anne, Brooks, James D., Gnanapragasam, Vincent J., Stoyanova, Tanya
Foilsithe in Br J Cancer (2020)

Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia

le Tseng, Yu-Chou, Kulp, Samuel K., Lai, I-Lu, Hsu, En-Chi, He, Wei A., Frankhouser, David E., Yan, Pearlly S., Mo, Xiaokui, Bloomston, Mark, Lesinski, Gregory B., Marcucci, Guido, Guttridge, Denis C., Bekaii-Saab, Tanios, Chen, Ching-Shih
Foilsithe in J Natl Cancer Inst (2015)

In vivo imaging of methionine aminopeptidase II for prostate cancer risk stratification

le Xie, Jinghang, Rice, Meghan A., Chen, Zixin, Cheng, Yunfeng, Hsu, En-Chi, Chen, Min, Song, Guosheng, Cui, Liyang, Zhou, Kaixiang, Castillo, Jessa B., Zhang, Chiyuan A., Shen, Bin, Chin, Frederick T., Kunder, Christian A., Brooks, James D., Stoyanova, Tanya, Rao, Jianghong
Foilsithe in Cancer Res (2021)

Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer

le Hsu, En-Chi, Kulp, Samuel K., Huang, Han-Li, Tu, Huang-Ju, Chao, Min-Wu, Tseng, Yu-Chou, Yang, Ming-Chen, Salunke, Santosh B., Sullivan, Nicholas J., Chen, Wen-Chung, Zhang, Jianying, Teng, Che-Ming, Fu, Wen-Mei, Sun, Duxin, Wicha, Max S., Shapiro, Charles L., Chen, Ching-Shih
Foilsithe in Carcinogenesis (2016)

The Exosome Total Isolation Chip

le Liu, Fei, Vermesh, Ophir, Mani, Vigneshwaran, Ge, Tianjia J., Madsen, Steven J., Sabour, Andrew, Hsu, En-Chi, Gowrishankar, Gayatri, Kanada, Masamitsu, Jokerst, Jesse V., Sierra, Raymond G., Chang, Edwin, Lau, Kenneth, Sridhar, Kaushik, Bermudez, Abel, Pitteri, Sharon J., Stoyanova, Tanya, Sinclair, Robert, Nair, Viswam S., Gambhir, Sanjiv S., Demirci, Utkan
Foilsithe in ACS Nano (2017)

Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1

le Hsu, En-Chi, Rice, Meghan A., Bermudez, Abel, Marques, Fernando Jose Garcia, Aslan, Merve, Liu, Shiqin, Ghoochani, Ali, Zhang, Chiyuan Amy, Chen, Yun-Sheng, Zlitni, Aimen, Kumar, Sahil, Nolley, Rosalie, Habte, Frezghi, Shen, Michelle, Koul, Kashyap, Peehl, Donna M., Zoubeidi, Amina, Gambhir, Sanjiv S., Kunder, Christian A., Pitteri, Sharon J., Brooks, James D., Stoyanova, Tanya
Foilsithe in Proc Natl Acad Sci U S A (2020)

Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer

le Stoyanova, Tanya, Riedinger, Mireille, Lin, Shu, Faltermeier, Claire M., Smith, Bryan A., Zhang, Kelvin X., Going, Catherine C., Goldstein, Andrew S., Lee, John K., Drake, Justin M., Rice, Meghan A., Hsu, En-Chi, Nowroozizadeh, Behdokht, Castor, Brandon, Orellana, Sandra Y., Blum, Steven M., Cheng, Donghui, Pienta, Kenneth J., Reiter, Robert E., Pitteri, Sharon J., Huang, Jiaoti, Witte, Owen N.
Foilsithe in Proc Natl Acad Sci U S A (2016)