Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension

por Hiltunen, Timo P., Rimpelä, Jenni M., Mohney, Robert P., Stirdivant, Steven M., Kontula, Kimmo K.
Publicado en PLoS One (2017)

Effect of four classes of antihypertensive drugs on cardiac repolarization heterogeneity: A double-blind rotational study

por Sánez Tähtisalo, Heini, Hiltunen, Timo P., Kenttä, Tuomas, Junttila, Juhani, Oikarinen, Lasse, Virolainen, Juha, Kontula, Kimmo K., Porthan, Kimmo
Publicado en PLoS One (2020)

Elevated serum squalene and cholesterol synthesis markers in pregnant obese women with gestational diabetes mellitus(1)

por Miettinen, Helena E., Rönö, Kristiina, Koivusalo, Saila, Stach-Lempinen, Beata, Pöyhönen-Alho, Maritta, Eriksson, Johan G., Hiltunen, Timo P., Gylling, Helena
Publicado en J Lipid Res (2014)

Human essential hypertension: no significant association of polygenic risk scores with antihypertensive drug responses

por Sánez Tähtisalo, Heini, Ruotsalainen, Sanni, Mars, Nina, Porthan, Kimmo, Oikarinen, Lasse, Virolainen, Juha, Fyhrquist, Frej, Ripatti, Samuli, Kontula, Kimmo K., Hiltunen, Timo P.
Publicado en Sci Rep (2020)

Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients

por Rimpelä, Jenni M., Pörsti, Ilkka H., Jula, Antti, Lehtimäki, Terho, Niiranen, Teemu J., Oikarinen, Lasse, Porthan, Kimmo, Tikkakoski, Antti, Virolainen, Juha, Kontula, Kimmo K., Hiltunen, Timo P.
Publicado en BMC Med Genet (2018)

Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension

por Hannila-Handelberg, Tuula, Kontula, Kimmo, Tikkanen, Ilkka, Tikkanen, Tuula, Fyhrquist, Frej, Helin, Karri, Fodstad, Heidi, Piippo, Kirsi, Miettinen, Helena E, Virtamo, Jarmo, Krusius, Tom, Sarna, Seppo, Gautschi, Ivan, Schild, Laurent, Hiltunen, Timo P
Publicado 2005

Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo‐Controlled Cross‐Over Study, Using Four Classes of Antihypertensive Drugs

por Hiltunen, Timo P., Donner, Kati M., Sarin, Antti‐Pekka, Saarela, Janna, Ripatti, Samuli, Chapman, Arlene B., Gums, John G., Gong, Yan, Cooper‐DeHoff, Rhonda M., Frau, Francesca, Glorioso, Valeria, Zaninello, Roberta, Salvi, Erika, Glorioso, Nicola, Boerwinkle, Eric, Turner, Stephen T., Johnson, Julie A., Kontula, Kimmo K.
Publicado en J Am Heart Assoc (2015)

Genome‐Wide Meta‐Analysis of Blood Pressure Response to β(1)‐Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)

por Singh, Sonal, Warren, Helen R., Hiltunen, Timo P., McDonough, Caitrin W., El Rouby, Nihal, Salvi, Erika, Wang, Zhiying, Garofalidou, Tatiana, Fyhrquist, Frej, Kontula, Kimmo K., Glorioso, Valeria, Zaninello, Roberta, Glorioso, Nicola, Pepine, Carl J., Munroe, Patricia B., Turner, Stephan T., Chapman, Arlene B., Boerwinkle, Eric, Johnson, Julie A., Gong, Yan, Cooper‐DeHoff, Rhonda M.
Publicado en J Am Heart Assoc (2019)

GENOME-WIDE AND GENE-BASED META-ANALYSES IDENTIFY NOVEL LOCI INFLUENCING BLOOD PRESSURE RESPONSE TO HYDROCHLOROTHIAZIDE

por Salvi, Erika, Wang, Zhiying, Rizzi, Federica, Gong, Yan, McDonough, Caitrin W., Padmanabhan, Sandosh, Hiltunen, Timo P., Lanzani, Chiara, Zaninello, Roberta, Chittani, Martina, Bailey, Kent R., Sarin, Antti-Pekka, Barcella, Matteo, Melander, Olle, Chapman, Arlene B., Manunta, Paolo, Kontula, Kimmo K., Glorioso, Nicola, Cusi, Daniele, Dominiczak, Anna F., Johnson, Julie A., Barlassina, Cristina, Boerwinkle, Eric, Cooper-DeHoff, Rhonda M., Turner, Stephen T.
Publicado en Hypertension (2016)

Genomic Association Analysis of Common Variants Influencing Antihypertensive Response to Hydrochlorothiazide

por Turner, Stephen T., Boerwinkle, Eric, O'Connell, Jeffrey R., Bailey, Kent R., Gong, Yan, Chapman, Arlene B., McDonough, Caitrin W., Beitelshees, Amber L., Schwartz, Gary L., Gums, John G., Padmanabhan, Sandosh, Hiltunen, Timo P., Citterio, Lorena, Donner, Kati M., Hedner, Thomas, Lanzani, Chiara, Melander, Olle, Saarela, Janna, Ripatti, Samuli, Wahlstrand, Björn, Manunta, Paolo, Kontula, Kimmo, Dominiczak, Anna F., Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Publicado 2013

PTPRD gene associated with blood pressure response to atenolol and resistant hypertension

por Gong, Yan, McDonough, Caitrin W., Beitelshees, Amber L., Rouby, Nihal El, Hiltunen, Timo P., O’Connell, Jeffrey R., Padmanabhan, Sandosh, Langaee, Taimour Y., Hall, Karen, Schmidt, Siegfried O.F., Curry, Robert W., Gums, John G., Donner, Kati M., Kontula, Kimmo K., Bailey, Kent R., Boerwinkle, Eric, Takahashi, Atsushi, Tanaka, Toshihiro, Kubo, Michiaki, Chapman, Arlene B., Turner, Stephen T., Pepine, Carl J., Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Publicado en J Hypertens (2015)

TET2 and CSMD1genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives

por Chittani, Martina, Zaninello, Roberta, Lanzani, Chiara, Frau, Francesca, Ortu, Maria F., Salvi, Erika, Fresu, Giovanni, Citterio, Lorena, Braga, Daniele, Piras, Daniela A., Carpini, Simona Delli, Velayutham, Dinesh, Simonini, Marco, Argiolas, Giuseppe, Pozzoli, Simona, Troffa, Chiara, Glorioso, Valeria, Kontula, Kimmo K., Hiltunen, Timo P., Donner, Kati M., Turner, Stephen T., Boerwinkle, Eric, Chapman, Arlene B., Padmanabhan, Sandosh, Dominiczak, Anna F., Melander, Olle, Johnson, Julie A., Cooper-Dehoff, Rhonda M, Gong, Yan, Rivera, Natalia V., Condorelli, Gianluigi, Trimarco, Bruno, Manunta, Paolo, Cusi, Daniele, Glorioso, Nicola, Barlassina, Cristina
Publicado en J Hypertens (2015)