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Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension

OBJECTIVE: In order to search for metabolic biomarkers of antihypertensive drug responsiveness, we measured >600 biochemicals in plasma samples of subjects participating in the GENRES Study. Hypertensive men received in a double-blind rotational fashion amlodipine, bisoprolol, hydrochlorothiazide...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hiltunen, Timo P., Rimpelä, Jenni M., Mohney, Robert P., Stirdivant, Steven M., Kontula, Kimmo K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679533/
https://ncbi.nlm.nih.gov/pubmed/29121091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187729
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