Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension

par Hiltunen, Timo P., Rimpelä, Jenni M., Mohney, Robert P., Stirdivant, Steven M., Kontula, Kimmo K.
Publié dans PLoS One (2017)

Effect of four classes of antihypertensive drugs on cardiac repolarization heterogeneity: A double-blind rotational study

par Sánez Tähtisalo, Heini, Hiltunen, Timo P., Kenttä, Tuomas, Junttila, Juhani, Oikarinen, Lasse, Virolainen, Juha, Kontula, Kimmo K., Porthan, Kimmo
Publié dans PLoS One (2020)

Elevated serum squalene and cholesterol synthesis markers in pregnant obese women with gestational diabetes mellitus(1)

par Miettinen, Helena E., Rönö, Kristiina, Koivusalo, Saila, Stach-Lempinen, Beata, Pöyhönen-Alho, Maritta, Eriksson, Johan G., Hiltunen, Timo P., Gylling, Helena
Publié dans J Lipid Res (2014)

Human essential hypertension: no significant association of polygenic risk scores with antihypertensive drug responses

par Sánez Tähtisalo, Heini, Ruotsalainen, Sanni, Mars, Nina, Porthan, Kimmo, Oikarinen, Lasse, Virolainen, Juha, Fyhrquist, Frej, Ripatti, Samuli, Kontula, Kimmo K., Hiltunen, Timo P.
Publié dans Sci Rep (2020)

Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients

par Rimpelä, Jenni M., Pörsti, Ilkka H., Jula, Antti, Lehtimäki, Terho, Niiranen, Teemu J., Oikarinen, Lasse, Porthan, Kimmo, Tikkakoski, Antti, Virolainen, Juha, Kontula, Kimmo K., Hiltunen, Timo P.
Publié dans BMC Med Genet (2018)

Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension

par Hannila-Handelberg, Tuula, Kontula, Kimmo, Tikkanen, Ilkka, Tikkanen, Tuula, Fyhrquist, Frej, Helin, Karri, Fodstad, Heidi, Piippo, Kirsi, Miettinen, Helena E, Virtamo, Jarmo, Krusius, Tom, Sarna, Seppo, Gautschi, Ivan, Schild, Laurent, Hiltunen, Timo P
Publié 2005

Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo‐Controlled Cross‐Over Study, Using Four Classes of Antihypertensive Drugs

par Hiltunen, Timo P., Donner, Kati M., Sarin, Antti‐Pekka, Saarela, Janna, Ripatti, Samuli, Chapman, Arlene B., Gums, John G., Gong, Yan, Cooper‐DeHoff, Rhonda M., Frau, Francesca, Glorioso, Valeria, Zaninello, Roberta, Salvi, Erika, Glorioso, Nicola, Boerwinkle, Eric, Turner, Stephen T., Johnson, Julie A., Kontula, Kimmo K.
Publié dans J Am Heart Assoc (2015)

Genome‐Wide Meta‐Analysis of Blood Pressure Response to β(1)‐Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)

par Singh, Sonal, Warren, Helen R., Hiltunen, Timo P., McDonough, Caitrin W., El Rouby, Nihal, Salvi, Erika, Wang, Zhiying, Garofalidou, Tatiana, Fyhrquist, Frej, Kontula, Kimmo K., Glorioso, Valeria, Zaninello, Roberta, Glorioso, Nicola, Pepine, Carl J., Munroe, Patricia B., Turner, Stephan T., Chapman, Arlene B., Boerwinkle, Eric, Johnson, Julie A., Gong, Yan, Cooper‐DeHoff, Rhonda M.
Publié dans J Am Heart Assoc (2019)

GENOME-WIDE AND GENE-BASED META-ANALYSES IDENTIFY NOVEL LOCI INFLUENCING BLOOD PRESSURE RESPONSE TO HYDROCHLOROTHIAZIDE

par Salvi, Erika, Wang, Zhiying, Rizzi, Federica, Gong, Yan, McDonough, Caitrin W., Padmanabhan, Sandosh, Hiltunen, Timo P., Lanzani, Chiara, Zaninello, Roberta, Chittani, Martina, Bailey, Kent R., Sarin, Antti-Pekka, Barcella, Matteo, Melander, Olle, Chapman, Arlene B., Manunta, Paolo, Kontula, Kimmo K., Glorioso, Nicola, Cusi, Daniele, Dominiczak, Anna F., Johnson, Julie A., Barlassina, Cristina, Boerwinkle, Eric, Cooper-DeHoff, Rhonda M., Turner, Stephen T.
Publié dans Hypertension (2016)

Genomic Association Analysis of Common Variants Influencing Antihypertensive Response to Hydrochlorothiazide

par Turner, Stephen T., Boerwinkle, Eric, O'Connell, Jeffrey R., Bailey, Kent R., Gong, Yan, Chapman, Arlene B., McDonough, Caitrin W., Beitelshees, Amber L., Schwartz, Gary L., Gums, John G., Padmanabhan, Sandosh, Hiltunen, Timo P., Citterio, Lorena, Donner, Kati M., Hedner, Thomas, Lanzani, Chiara, Melander, Olle, Saarela, Janna, Ripatti, Samuli, Wahlstrand, Björn, Manunta, Paolo, Kontula, Kimmo, Dominiczak, Anna F., Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Publié 2013

PTPRD gene associated with blood pressure response to atenolol and resistant hypertension

par Gong, Yan, McDonough, Caitrin W., Beitelshees, Amber L., Rouby, Nihal El, Hiltunen, Timo P., O’Connell, Jeffrey R., Padmanabhan, Sandosh, Langaee, Taimour Y., Hall, Karen, Schmidt, Siegfried O.F., Curry, Robert W., Gums, John G., Donner, Kati M., Kontula, Kimmo K., Bailey, Kent R., Boerwinkle, Eric, Takahashi, Atsushi, Tanaka, Toshihiro, Kubo, Michiaki, Chapman, Arlene B., Turner, Stephen T., Pepine, Carl J., Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Publié dans J Hypertens (2015)

TET2 and CSMD1genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives

par Chittani, Martina, Zaninello, Roberta, Lanzani, Chiara, Frau, Francesca, Ortu, Maria F., Salvi, Erika, Fresu, Giovanni, Citterio, Lorena, Braga, Daniele, Piras, Daniela A., Carpini, Simona Delli, Velayutham, Dinesh, Simonini, Marco, Argiolas, Giuseppe, Pozzoli, Simona, Troffa, Chiara, Glorioso, Valeria, Kontula, Kimmo K., Hiltunen, Timo P., Donner, Kati M., Turner, Stephen T., Boerwinkle, Eric, Chapman, Arlene B., Padmanabhan, Sandosh, Dominiczak, Anna F., Melander, Olle, Johnson, Julie A., Cooper-Dehoff, Rhonda M, Gong, Yan, Rivera, Natalia V., Condorelli, Gianluigi, Trimarco, Bruno, Manunta, Paolo, Cusi, Daniele, Glorioso, Nicola, Barlassina, Cristina
Publié dans J Hypertens (2015)