Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension

by Hiltunen, Timo P., Rimpelä, Jenni M., Mohney, Robert P., Stirdivant, Steven M., Kontula, Kimmo K.
Published in PLoS One (2017)

Effect of four classes of antihypertensive drugs on cardiac repolarization heterogeneity: A double-blind rotational study

by Sánez Tähtisalo, Heini, Hiltunen, Timo P., Kenttä, Tuomas, Junttila, Juhani, Oikarinen, Lasse, Virolainen, Juha, Kontula, Kimmo K., Porthan, Kimmo
Published in PLoS One (2020)

Elevated serum squalene and cholesterol synthesis markers in pregnant obese women with gestational diabetes mellitus(1)

by Miettinen, Helena E., Rönö, Kristiina, Koivusalo, Saila, Stach-Lempinen, Beata, Pöyhönen-Alho, Maritta, Eriksson, Johan G., Hiltunen, Timo P., Gylling, Helena
Published in J Lipid Res (2014)

Human essential hypertension: no significant association of polygenic risk scores with antihypertensive drug responses

by Sánez Tähtisalo, Heini, Ruotsalainen, Sanni, Mars, Nina, Porthan, Kimmo, Oikarinen, Lasse, Virolainen, Juha, Fyhrquist, Frej, Ripatti, Samuli, Kontula, Kimmo K., Hiltunen, Timo P.
Published in Sci Rep (2020)

Genome-wide association study of nocturnal blood pressure dipping in hypertensive patients

by Rimpelä, Jenni M., Pörsti, Ilkka H., Jula, Antti, Lehtimäki, Terho, Niiranen, Teemu J., Oikarinen, Lasse, Porthan, Kimmo, Tikkakoski, Antti, Virolainen, Juha, Kontula, Kimmo K., Hiltunen, Timo P.
Published in BMC Med Genet (2018)

Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension

by Hannila-Handelberg, Tuula, Kontula, Kimmo, Tikkanen, Ilkka, Tikkanen, Tuula, Fyhrquist, Frej, Helin, Karri, Fodstad, Heidi, Piippo, Kirsi, Miettinen, Helena E, Virtamo, Jarmo, Krusius, Tom, Sarna, Seppo, Gautschi, Ivan, Schild, Laurent, Hiltunen, Timo P
Published 2005

Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo‐Controlled Cross‐Over Study, Using Four Classes of Antihypertensive Drugs

by Hiltunen, Timo P., Donner, Kati M., Sarin, Antti‐Pekka, Saarela, Janna, Ripatti, Samuli, Chapman, Arlene B., Gums, John G., Gong, Yan, Cooper‐DeHoff, Rhonda M., Frau, Francesca, Glorioso, Valeria, Zaninello, Roberta, Salvi, Erika, Glorioso, Nicola, Boerwinkle, Eric, Turner, Stephen T., Johnson, Julie A., Kontula, Kimmo K.
Published in J Am Heart Assoc (2015)

Genome‐Wide Meta‐Analysis of Blood Pressure Response to β(1)‐Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)

by Singh, Sonal, Warren, Helen R., Hiltunen, Timo P., McDonough, Caitrin W., El Rouby, Nihal, Salvi, Erika, Wang, Zhiying, Garofalidou, Tatiana, Fyhrquist, Frej, Kontula, Kimmo K., Glorioso, Valeria, Zaninello, Roberta, Glorioso, Nicola, Pepine, Carl J., Munroe, Patricia B., Turner, Stephan T., Chapman, Arlene B., Boerwinkle, Eric, Johnson, Julie A., Gong, Yan, Cooper‐DeHoff, Rhonda M.
Published in J Am Heart Assoc (2019)

GENOME-WIDE AND GENE-BASED META-ANALYSES IDENTIFY NOVEL LOCI INFLUENCING BLOOD PRESSURE RESPONSE TO HYDROCHLOROTHIAZIDE

by Salvi, Erika, Wang, Zhiying, Rizzi, Federica, Gong, Yan, McDonough, Caitrin W., Padmanabhan, Sandosh, Hiltunen, Timo P., Lanzani, Chiara, Zaninello, Roberta, Chittani, Martina, Bailey, Kent R., Sarin, Antti-Pekka, Barcella, Matteo, Melander, Olle, Chapman, Arlene B., Manunta, Paolo, Kontula, Kimmo K., Glorioso, Nicola, Cusi, Daniele, Dominiczak, Anna F., Johnson, Julie A., Barlassina, Cristina, Boerwinkle, Eric, Cooper-DeHoff, Rhonda M., Turner, Stephen T.
Published in Hypertension (2016)

Genomic Association Analysis of Common Variants Influencing Antihypertensive Response to Hydrochlorothiazide

by Turner, Stephen T., Boerwinkle, Eric, O'Connell, Jeffrey R., Bailey, Kent R., Gong, Yan, Chapman, Arlene B., McDonough, Caitrin W., Beitelshees, Amber L., Schwartz, Gary L., Gums, John G., Padmanabhan, Sandosh, Hiltunen, Timo P., Citterio, Lorena, Donner, Kati M., Hedner, Thomas, Lanzani, Chiara, Melander, Olle, Saarela, Janna, Ripatti, Samuli, Wahlstrand, Björn, Manunta, Paolo, Kontula, Kimmo, Dominiczak, Anna F., Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Published 2013

PTPRD gene associated with blood pressure response to atenolol and resistant hypertension

by Gong, Yan, McDonough, Caitrin W., Beitelshees, Amber L., Rouby, Nihal El, Hiltunen, Timo P., O’Connell, Jeffrey R., Padmanabhan, Sandosh, Langaee, Taimour Y., Hall, Karen, Schmidt, Siegfried O.F., Curry, Robert W., Gums, John G., Donner, Kati M., Kontula, Kimmo K., Bailey, Kent R., Boerwinkle, Eric, Takahashi, Atsushi, Tanaka, Toshihiro, Kubo, Michiaki, Chapman, Arlene B., Turner, Stephen T., Pepine, Carl J., Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Published in J Hypertens (2015)

TET2 and CSMD1genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives

by Chittani, Martina, Zaninello, Roberta, Lanzani, Chiara, Frau, Francesca, Ortu, Maria F., Salvi, Erika, Fresu, Giovanni, Citterio, Lorena, Braga, Daniele, Piras, Daniela A., Carpini, Simona Delli, Velayutham, Dinesh, Simonini, Marco, Argiolas, Giuseppe, Pozzoli, Simona, Troffa, Chiara, Glorioso, Valeria, Kontula, Kimmo K., Hiltunen, Timo P., Donner, Kati M., Turner, Stephen T., Boerwinkle, Eric, Chapman, Arlene B., Padmanabhan, Sandosh, Dominiczak, Anna F., Melander, Olle, Johnson, Julie A., Cooper-Dehoff, Rhonda M, Gong, Yan, Rivera, Natalia V., Condorelli, Gianluigi, Trimarco, Bruno, Manunta, Paolo, Cusi, Daniele, Glorioso, Nicola, Barlassina, Cristina
Published in J Hypertens (2015)