Enhanced anti-tumor activity of the glycoengineered type II CD20 antibody obinutuzumab (GA101) in combination with chemotherapy in xenograft models of human lymphoma

par Herting, Frank, Friess, Thomas, Bader, Sabine, Muth, Gunter, Hölzlwimmer, Gabriele, Rieder, Natascha, Umana, Pablo, Klein, Christian
Publié 2014

Autocrine VEGFR1 and VEGFR2 signaling promotes survival in human glioblastoma models in vitro and in vivo

par Szabo, Emese, Schneider, Hannah, Seystahl, Katharina, Rushing, Elisabeth Jane, Herting, Frank, Weidner, K. Michael, Weller, Michael
Publié dans Neuro Oncol (2016)

GA101 P329GLALA, a variant of obinutuzumab with abolished ADCC, ADCP and CDC function but retained cell death induction, is as efficient as rituximab in B-cell depletion and antitu...

par Herter, Sylvia, Herting, Frank, Muth, Gunter, van Puijenbroek, Erwin, Schlothauer, Tilman, Ferrara, Claudia, Brady, Kevin, Lang, Sabine, Bacac, Marina, Mössner, Ekkehard, Umana, Pablo, Klein, Christian
Publié dans Haematologica (2018)

Vaccine-induced CD8 T cells are redirected with peptide-MHC class I-IgG antibody fusion proteins to eliminate tumor cells in vivo

par Fischer, Cornelia, Munks, Michael W., Hill, Ann B., Kroczek, Richard A., Bissinger, Stefan, Brand, Verena, Schmittnaegel, Martina, Imhof-Jung, Sabine, Hoffmann, Eike, Herting, Frank, Klein, Christian, Knoetgen, Hendrik
Publié dans MAbs (2020)

An integrated approach to quantitative modelling in angiogenesis research

par Connor, Anthony J., Nowak, Radosław P., Lorenzon, Erica, Thomas, Markus, Herting, Frank, Hoert, Stefan, Quaiser, Tom, Shochat, Eliezer, Pitt-Francis, Joe, Cooper, Jonathan, Maini, Philip K., Byrne, Helen M.
Publié dans J R Soc Interface (2015)

A re-engineered immunotoxin shows promising preclinical activity in ovarian cancer

par Kollmorgen, Gwendlyn, Palme, Klara, Seidl, Annette, Scheiblich, Stefan, Birzele, Fabian, Wilson, Sabine, Clemens, Christian, Voss, Edgar, Kaufmann, Martin, Hirzel, Klaus, Rieder, Natascha, Krippendorff, Ben-Fillippo, Herting, Frank, Niederfellner, Gerhard
Publié dans Sci Rep (2017)

A Novel Angiopoietin-2 Selective Fully Human Antibody with Potent Anti-Tumoral and Anti-Angiogenic Efficacy and Superior Side Effect Profile Compared to Pan-Angiopoietin-1/-2 Inhib...

par Thomas, Markus, Kienast, Yvonne, Scheuer, Werner, Bähner, Monika, Kaluza, Klaus, Gassner, Christian, Herting, Frank, Brinkmann, Ulrich, Seeber, Stefan, Kavlie, Anita, Welschof, Martin, Ries, Stefan, Weidner, K. Michael, Regula, Jörg T., Klein, Christian
Publié 2013

Impact of selective anti‐BMP9 treatment on tumor cells and tumor angiogenesis

par Brand, Verena, Lehmann, Christian, Umkehrer, Christian, Bissinger, Stefan, Thier, Martina, de Wouters, Mariana, Raemsch, Romi, Jucknischke, Ute, Haas, Alexander, Breuer, Sebastian, Birzele, Fabian, Racek, Tomas, Reis, Marco, Lorenzon, Erica, Herting, Frank, Stürzl, Michael, Lorenz, Stefan, Kienast, Yvonne
Publié dans Mol Oncol (2016)

Characterization of a re‐engineered, mesothelin‐targeted Pseudomonas exotoxin fusion protein for lung cancer therapy

par Bauss, Frieder, Lechmann, Martin, Krippendorff, Ben-Fillippo, Staack, Roland, Herting, Frank, Festag, Matthias, Imhof-Jung, Sabine, Hesse, Friederike, Pompiati, Marc, Kollmorgen, Gwendlyn, da Silva Mateus Seidl, Rita, Bossenmaier, Birgit, Lau, Wilma, Schantz, Christian, Stracke, Jan O., Brinkmann, Ulrich, Onda, Masanori, Pastan, Ira, Bosslet, Klaus, Niederfellner, Gerhard
Publié dans Mol Oncol (2016)

Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy

par Kashyap, Abhishek S., Schmittnaegel, Martina, Rigamonti, Nicolò, Pais-Ferreira, Daniela, Mueller, Philipp, Buchi, Melanie, Ooi, Chia-Huey, Kreuzaler, Matthias, Hirschmann, Petra, Guichard, Alan, Rieder, Natascha, Bill, Ruben, Herting, Frank, Kienast, Yvonne, Dirnhofer, Stefan, Klein, Christian, Hoves, Sabine, Ries, Carola H., Corse, Emily, De Palma, Michele, Zippelius, Alfred
Publié dans Proc Natl Acad Sci U S A (2020)