Target-mediated drug disposition and prolonged liver accumulation of a novel humanized anti-CD81 monoclonal antibody in cynomolgus monkeys

Por Vexler, Vladimir, Yu, Li, Pamulapati, Chandrasena, Garrido, Rosario, Grimm, Hans Peter, Sriraman, Priya, Bohini, Sandhya, Schraeml, Michael, Singh, Usha, Brandt, Michael, Ries, Stefan, Ma, Han, Klumpp, Klaus, Ji, Changhua
Publicado em 2013

A Novel Angiopoietin-2 Selective Fully Human Antibody with Potent Anti-Tumoral and Anti-Angiogenic Efficacy and Superior Side Effect Profile Compared to Pan-Angiopoietin-1/-2 Inhib...

Por Thomas, Markus, Kienast, Yvonne, Scheuer, Werner, Bähner, Monika, Kaluza, Klaus, Gassner, Christian, Herting, Frank, Brinkmann, Ulrich, Seeber, Stefan, Kavlie, Anita, Welschof, Martin, Ries, Stefan, Weidner, K. Michael, Regula, Jörg T., Klein, Christian
Publicado em 2013

A Novel Glycoengineered Bispecific Antibody Format for Targeted Inhibition of Epidermal Growth Factor Receptor (EGFR) and Insulin-like Growth Factor Receptor Type I (IGF-1R) Demons...

Por Schanzer, Juergen M., Wartha, Katharina, Croasdale, Rebecca, Moser, Samuel, Künkele, Klaus-Peter, Ries, Carola, Scheuer, Werner, Duerr, Harald, Pompiati, Sandra, Pollman, Jan, Stracke, Jan, Lau, Wilma, Ries, Stefan, Brinkmann, Ulrich, Klein, Christian, Umana, Pablo
Publicado em 2014