Elimination of a cholecystokinin receptor agonist “trigger” in an effort to develop positive allosteric modulators without intrinsic agonist activity

بواسطة Desai, Aditya J., Henke, Brad R., Miller, Laurence J.
الحاوية / القاعدة Bioorg Med Chem Lett (2015)

Structural determinants driving homoserine lactone ligand selection in the Pseudomonas aeruginosa LasR quorum-sensing receptor

بواسطة McCready, Amelia R., Paczkowski, Jon E., Henke, Brad R., Bassler, Bonnie L.
الحاوية / القاعدة Proc Natl Acad Sci U S A (2019)

Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein–Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor...

بواسطة Taylor, Isabelle R., Paczkowski, Jon E., Jeffrey, Philip D., Henke, Brad R., Smith, Chari D., Bassler, Bonnie L.
الحاوية / القاعدة ACS Chem Biol (2021)

Mechanism underlying autoinducer recognition in the Vibrio cholerae DPO-VqmA quorum-sensing pathway

بواسطة Huang, Xiuliang, Duddy, Olivia P., Silpe, Justin E., Paczkowski, Jon E., Cong, Jianping, Henke, Brad R., Bassler, Bonnie L.
الحاوية / القاعدة J Biol Chem (2020)

Flavonoids Suppress Pseudomonas aeruginosa Virulence through Allosteric Inhibition of Quorum-sensing Receptors

بواسطة Paczkowski, Jon E., Mukherjee, Sampriti, McCready, Amelia R., Cong, Jian-Ping, Aquino, Christopher J., Kim, Hahn, Henke, Brad R., Smith, Chari D., Bassler, Bonnie L.
الحاوية / القاعدة J Biol Chem (2017)

Discovery of PqsE Thioesterase Inhibitors for Pseudomonas aeruginosa using DNA-Encoded Small Molecule Library Screening

بواسطة Valastyan, Julie S., Tota, Michael R., Taylor, Isabelle R., Stergioula, Vasiliki, Hone, Graham A.B., Smith, Chari D., Henke, Brad R., Carson, Kenneth G., Bassler, Bonnie L.
الحاوية / القاعدة ACS Chem Biol (2020)

Molecular Basis for Benzodiazepine Agonist Action at the Type 1 Cholecystokinin Receptor

بواسطة Harikumar, Kaleeckal G., Cawston, Erin E., Lam, Polo C. H., Patil, Achyut, Orry, Andrew, Henke, Brad R., Abagyan, Ruben, Christopoulos, Arthur, Sexton, Patrick M., Miller, Laurence J.
منشور في 2013

An autoinducer analog reveals an alternative mode of ligand binding for the LasR quorum-sensing receptor

بواسطة Paczkowski, Jon E., McCready, Amelia R., Cong, Jian-Ping, Li, Zhijie, Jeffrey, Philip D., Smith, Chari D., Henke, Brad R., Hughson, Frederick M., Bassler, Bonnie L.
الحاوية / القاعدة ACS Chem Biol (2019)