An autoinducer analog reveals an alternative mode of ligand binding for the LasR quorum-sensing receptor

Bacteria use a cell-cell communication process called quorum sensing to coordinate collective behaviors. Quorum sensing relies on production and group-wide detection of extracellular signal molecules called autoinducers. Here, we probe the activity of the Pseudomonas aeruginosa LasR quorum-sensing r...

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Vydáno v:ACS Chem Biol
Hlavní autoři: Paczkowski, Jon E., McCready, Amelia R., Cong, Jian-Ping, Li, Zhijie, Jeffrey, Philip D., Smith, Chari D., Henke, Brad R., Hughson, Frederick M., Bassler, Bonnie L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601336/
https://ncbi.nlm.nih.gov/pubmed/30763066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00971
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